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US 9,526,700 B2Granted
Composition for inactivating an enveloped virus
AssigneeViroblock S.A.
InventorsThierry Pelet, Donald F. H. Wallach
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Abstract
The present invention relates generally to the field of prevention of diseases caused by enveloped viruses. More particularly, this invention concerns a composition for inactivating an enveloped virus comprising at least one non phospholipid Lipid Vesicle (nPLV) able to interact with said enveloped virus and an agent that enhances the lipid exchange between said nPLV and the membrane of said enveloped virus.
Claims13
A method for inactivating an enveloped virus, said method comprising contacting an enveloped virus with an effective amount of a composition comprising
- (a) at least one cholesterol-free, non-phospholipid Lipid Vesicle (nPLV);
- and
- (b) between about 0.1 mM to about 10 mM of an agent selected from the group consisting of:
- α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, dimethyl-β-cyclodextrin, trimethyl-β-cyclodextrin, randomly methylated-β-cyclodextrin, hydroxyethyl-β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin, 3-hydroxypropyl-β-cyclodextrin, 2,3-dihydroxypropyl-β-cyclodextrin, 2-hydroxyisobutyl-β-cyclodextrin, sulphobutylether-β-cyclodextrin, glucosyl-β-cyclodextrin, maltosyl-β-cyclodextrin and a combination thereof.
1 more element
Dependencies are inferred from the claim text.