# US 9,517,331 B2 · Iontophoresis patch

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- Number: US 9,517,331 B2
- Document ID: US9517331B2
- Status: Granted
- Kind: B2
- Application number: 13/578,168
- Filed: 2011-02-09
- Published: 2012-12-06
- Granted: 2016-12-13
- Earliest claimed: 2010-02-12
- Assignees: Terumo Kabushiki Kaisha; Teikoku Seiyaku Co., Ltd.
- Applicants: Mitsutoshi Yaegashi; Akihiro Hasui; Hiroyuki Kubo
- Inventors: Mitsutoshi Yaegashi; Akihiro Hasui; Hiroyuki Kubo
- Web page: https://patentgrep.com/patent/US9517331B2

## CPC

- A61N 1/0428: {Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

An iontophoresis patch is equipped with a donor gel and a reference gel which are disposed to contact an external conductor, for example, the skin of a patient and thereby output current from a current-carrying device to the external conductor. The iontophoresis patch includes: a donor portion having the donor gel containing a medical agent to be penetrated into the external conductor; a reference portion having a reference gel, mounted with the current-carrying device on the surface on the side opposite to the reference gel, and disposed on the external conductor apart from the donor portion; and an electrode film for supplying current from the current-carrying device to the donor gel and the reference gel.

## Claims

### Claim 1

An iontophoresis patch having a first contact member and a second contact member for outputting an electric current from an energizing unit to an external conductor upon being placed in contact with the external conductor, comprising:
a donor portion having the first contact member, the first contact member containing a drug to permeate into the external conductor;
a reference portion having the second contact member and which is placed on the external conductor away from the donor portion;
an electrode body having a flexible base, and a first electrode and a second electrode which are disposed on the base, for supplying electric currents from the energizing unit respectively to the first contact member and the second contact member, the electrode body being disposed over the donor portion and the reference portion;
a pair of connection terminals through which the energizing unit is disposed on the iontophoresis patch and which are electrically connected to the first electrode and the second electrode, wherein the pair of connection terminals are disposed on only the reference portion;
wherein the electrode body has a one-sided interconnect structure in the donor portion wherein the first electrode is disposed on a surface of the base that faces the external conductor; and
the electrode body has a double-sided interconnect structure in the reference portion wherein after the second electrode and a first contact terminal line and a second contact terminal line for interconnecting the pair of connection terminals and the first electrode and the second electrode are formed on the same surface of the base as the surface on which the first electrode is disposed, a portion of the base on which the first contact terminal line and the second contact terminal line are formed is folded back on itself into a two-layer structure, so that the second electrode is disposed on a surface of the reference portion that faces the external conductor, and terminal bases connected to the first contact terminal line and the second contact terminal line and also connected to the pair of connection terminals are disposed on a surface of the reference portion that is opposite to the surface thereof facing the external conductor.

### Claim 2 (depends on 1)

The iontophoresis patch according to claim 1, wherein the first contact terminal line and the second contact terminal line include wider portions disposed on a portion of the reference portion that includes a folding portion of the base, the wider portions being wider than other portions of the first contact terminal line and the second contact terminal line.

### Claim 3 (depends on 1)

The iontophoresis patch according to claim 1, wherein the electrode body includes a bridge portion interconnecting the donor portion and the reference portion.

### Claim 4 (depends on 3)

The iontophoresis patch according to claim 3, comprising:
a protective layer covering and electrically insulating the bridge portion.

### Claim 5 (depends on 1)

The iontophoresis patch according to claim 1, comprising:
a manually grippable grip projectingly formed on a side of at least one of the donor portion and the reference portion.

### Claim 6 (depends on 1)

The iontophoresis patch according to claim 1, wherein the donor portion has, on a surface thereof opposite to the first contact member, a central mark indicative of the center of the first contact member as viewed in plan, and an angle mark indicative of a rotational angle of the first contact member as viewed in plan.