# US 9,517,194 B2 · Oral care composition with cross-linked polymer peroxide

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 9,517,194 B2
- Document ID: US9517194B2
- Status: Granted
- Kind: B2
- Application number: 14/723,139
- Filed: 2015-05-27
- Published: 2015-09-17
- Granted: 2016-12-13
- Earliest claimed: 2004-08-27
- Assignees: Colgate-Palmolive Company
- Applicants: Colgate-Palmolive Company
- Inventors: Lynette A. Zaidel; Guisheng Pan; Suman K. Chopra; Prakasarao Mandadi; Michael Prencipe
- Web page: https://patentgrep.com/patent/US9517194B2

## CPC

- A61K 8/8176: {Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers}
- A61K 8/0208: {Tissues; Wipes; Patches}
- A61K 8/22: Peroxides; Oxygen; Ozone
- A61K 8/24: Phosphorous; Compounds thereof
- A61K 8/49: containing heterocyclic compounds
- A61K 8/817: {Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)}
- A61K 8/891: saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K 8/90: Block copolymers (A61K8/89 takes precedence)
- A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61Q 11/02: Preparations for deodorising, bleaching or disinfecting dentures
- A61K 2800/805: Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

## Claims

### Claim 1

An oral care composition comprising:
(a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer;
(b) a whitening agent;
(c) an orally acceptable carrier;
wherein the peroxide complex comprises a cross-linked polyvinyl pyrrolidone-peroxide complex wherein the whitening agent comprises hydrogen peroxide, and wherein said carrier comprises a block copolymer of ethylene oxide and propylene oxide;
wherein the composition further comprises tetrasodium pyrophosphate and calcium pyrophosphate.

### Claim 2 (depends on 1)

The composition of claim 1, further comprising polyethylene glycol.

### Claim 3 (depends on 1)

The composition of claim 1, wherein the peroxide complex is present at a level of 0.5% to 40%.

### Claim 4 (depends on 1)

The composition of claim 1, wherein the peroxide complex is present at a level of 20% to 30%.

### Claim 5 (depends on 1)

The composition of claim 1, wherein the peroxide complex comprises a peroxide component at a level of 1% to 25%.

### Claim 6 (depends on 1)

The composition of claim 1, wherein the peroxide complex comprises a peroxide component at a level of 5% to 18%.

### Claim 7 (depends on 1)

The composition of claim 1, wherein the molar ratio of the peroxide component to the cross-linked polyvinyl pyrrolidone is about 1:1.

### Claim 8 (depends on 2)

The composition of claim 2, wherein the polyethylene glycol is selected from PEG-200, PEG-300, PEG-400, PEG-600 and PEG-2000.

### Claim 9 (depends on 2)

The composition of claim 2, wherein the polyethylene glycol comprises PEG-600.