# US 9,517,122 B2 · Anti-migration micropatterned stent coating

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- Number: US 9,517,122 B2
- Document ID: US9517122B2
- Status: Granted
- Kind: B2
- Application number: 14/210,979
- Filed: 2014-03-14
- Published: 2014-09-18
- Granted: 2016-12-13
- Earliest claimed: 2013-03-15
- Assignees: Boston Scientific Scimed, Inc.
- Applicants: Boston Scientific Scimed, Inc.
- Inventors: Laura Elizabeth Firstenberg; Sean P. Fleury
- Web page: https://patentgrep.com/patent/US9517122B2

## CPC

- A61F 2/848: having means for fixation to the vessel wall, e.g. barbs
- A61F 2/0077: {Special surfaces of prostheses, e.g. for improving ingrowth (A61F2/30767 takes precedence)}
- A61F 2/04: Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts (A61F2/18, A61F2/20 take precedence; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95)
- A61F 2/06: Blood vessels
- A61F 2/064: {with special features to facilitate anastomotic coupling (anastomosis of natural blood vessels A61B17/11)}
- A61F 2/07: Stent-grafts
- A61F 2002/0081: {directly machined on the prosthetic surface, e.g. holes, grooves (A61F2/30771 takes precedence)}
- A61F 2002/044: {Oesophagi or esophagi or gullets}
- A61F 2002/072: {Encapsulated stents, e.g. wire or whole stent embedded in lining}
- A61F 2002/075: {the stent being loosely attached to the graft material, e.g. by stitching}
- A61F 2002/077: {having means to fill the space between stent-graft and aneurysm wall, e.g. a sleeve}
- A61F 2002/8483: {Barbs}
- A61F 2220/0008: Fixation appliances for connecting prostheses to the body
- A61F 2220/0016: with sharp anchoring protrusions, e.g. barbs, pins, spikes
- A61F 2250/0063: Nested prosthetic parts
- Y10T 156/10: Methods of surface bonding and/or assembly therefor
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

An endoprosthesis has an expanded state and an unexpanded state, the endoprosthesis includes a stent, wherein the stent has a first end, a second end, an inner surface defining a lumen, an outer surface, and a thickness defined between the inner surface and the outer surface; and a stent end covering disposed at one of the first and second ends, the stent end covering including a polymeric coating that includes a base and a plurality of protrusions, the base including a first major surface facing the outer surface of the stent, the base further including a second major surface from which each of the plurality of protrusions extends outwardly, the first major surface opposing the second major surface, wherein the protrusions are arranged in a micropattern. Methods of making and using an endoprosthesis are provided.

## Claims

### Claim 1

An endoprosthesis having an expanded state and an unexpanded state, the endoprosthesis comprising:
a stent, wherein the stent has a first end, a second end, and a longitudinal axis extending therebetween, the stent having an inner surface extending from the first end to the second end and defining a lumen, an outer surface extending from the first end to the second end, and a thickness defined between the inner surface and the outer surface; and
a stent end covering disposed at the first end of the stent and extending longitudinally beyond the first end of the stent and then doubling back into the lumen of the stent, the stent end covering comprising:
a polymeric coating comprising a base and a plurality of protrusions, the base comprising a first major surface facing radially inwardly, the base further comprising a second major surface from which each of the plurality of protrusions extends outwardly, the first major surface opposing the second major surface, wherein the protrusions are arranged in a micropattern, wherein the micropattern of protrusions of the stent end covering extends longitudinally beyond the first end of the stent.

### Claim 2 (depends on 1)

The endoprosthesis of claim 1, wherein the stent end covering is adhered to the outer surface of the stent.

### Claim 3 (depends on 1)

The endoprosthesis of claim 1, wherein the stent end covering is adhered to the inner surface of the stent.

### Claim 4 (depends on 1)

The endoprosthesis of claim 1, wherein the stent end covering extends circumferentially and entirely around the first end of the stent.

### Claim 5 (depends on 1)

The endoprosthesis of claim 1, wherein the stent end covering extends circumferentially and partially around the first end of the stent.

### Claim 6 (depends on 1)

The endoprosthesis of claim 1, wherein the stent end covering extends longitudinally from a location between the first and second ends to a location that is not between the first and second ends.

### Claim 7 (depends on 1)

The endoprosthesis of claim 1, wherein at least a first portion of the stent end covering has a radial thickness greater than the thickness of the stent at the first end of the stent.

### Claim 8 (depends on 7)

The endoprosthesis of claim 7, wherein at least a second portion of the stent end covering has a radial thickness less than the radial thickness of the first portion of the stent end covering.

### Claim 9 (depends on 1)

The endoprosthesis of claim 1, wherein the stent end covering is a first stent end covering, and the endoprosthesis further comprises:
a second stent end covering disposed at the second end of the stent.

### Claim 10 (depends on 9)

The endoprosthesis of claim 9, wherein:
the first stent end covering has a first end and a second end, the first end of the first stent end covering doubling back into the stent lumen forming a cushion around the first end of the stent;
the second stent end covering has a first end and a second end, the first end of the second stent end covering located beyond the second end of the stent; and
the second end of the first end covering is spaced apart from the second end of the second end covering.

### Claim 11

An endoprosthesis, comprising:
a stent, wherein the stent has a first end, a second end, and a longitudinal axis extending therebetween, the stent having an inner surface extending from the first end to the second end and defining a lumen, an outer surface extending from the first end to the second end, and a thickness defined between the inner surface and the outer surface; and
a stent end covering disposed at the first end of the stent, the stent end covering comprising:
a first end and a second end;
an inner surface and an outer surface, the inner surface facing radially inward, and
a plurality of protrusions extending outwardly from the outer surface and
wherein the protrusions are arranged in a micropattern; and
wherein the first end of the stent end covering extends longitudinally beyond the first end of the stent and then doubles back into the lumen, the first end of the stent end covering is located a first distance from the second end of the stent and the second end of the stent end covering is located a second distance from the second end of the stent, the second distance being less than the first distance; and
wherein the second end of the stent end covering is located intermediate the first and second ends of the stent.

### Claim 12 (depends on 11)

The endoprosthesis of claim 11, wherein the first end of the stent end covering that doubles back into the lumen forms a cushion around the first end of the stent.

### Claim 13 (depends on 12)

The endoprosthesis of claim 12, wherein the micropattern of protrusions of the stent end covering extends longitudinally beyond the first end of the stent.

### Claim 14 (depends on 11)

The endoprosthesis of claim 11, wherein the stent end covering is a first stent end covering, and the endoprosthesis further comprises:
a second stent end covering disposed at the second end of the stent.

### Claim 15 (depends on 14)

The endoprosthesis of claim 14, wherein:
the second stent end covering has a first end and a second end, wherein the first end of the second stent end covering is located a first distance from the first end of the stent and the second end of the second stent end covering is located a second distance from the first end of the stent, the second distance being less than the first distance; and
the second end of the first end covering is spaced apart from the second end of the second end covering.

### Claim 16 (depends on 15)

The endoprosthesis of claim 15, wherein a medial portion of the stent is exposed between the first stent end covering and the second stent end covering.

### Claim 17

An implantable medical device, comprising:
a stent having a first end, a second end, and a longitudinal axis extending therebetween the stent having an inner surface extending from the first end to the second end and defining a lumen, and an outer surface extending from the first end to the second end;
a first stent covering section disposed around a circumference of the stent, the first stent covering section comprising:
a first end and a second end,
an inner wall surface facing radially inwardly and an outer wall surface facing radially outwardly, and
a plurality of protrusions extend outwardly from the outer wall surface,
wherein the protrusions are arranged in a micropattern,
a second stent covering section disposed around the circumference of the stent, the second stent covering section comprising:
a first end and a second end,
an inner wall surface facing radially inwardly and an outer wall surface facing radially outwardly, and
a plurality of protrusions extending outwardly from the outer wall surface,
wherein the protrusions are arranged in a micropattern;
wherein the first stent covering section is longitudinally spaced away from the second stent covering section, wherein the first end of the first stent covering section extends longitudinally beyond the first end of the stent and then doubles back into the stent lumen.

### Claim 18 (depends on 17)

The implantable medical device of claim 17, wherein a medial portion of the stent is exposed between the first stent covering section and the second stent covering section.

### Claim 19 (depends on 18)

The implantable medical device of claim 18, wherein the first stent covering section is disposed at the first end of the stent and the second stent covering section is disposed at the second end of the stent.

### Claim 20 (depends on 17)

The implantable medical device of claim 17, wherein:
the first end of the first stent covering section that doubles back into the stent lumen forms a cushion around the stent terminal end point;
the first end of the second stent covering section is located beyond the second end of the stent; and
the second end of the first end covering is spaced apart from the second end of the second end covering.
