# US 9,517,040 B2 · Method and system for providing information from a patient-specific model of blood flow > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,517,040 B2 - Document ID: US9517040B2 - Status: Granted - Kind: B2 - Application number: 14/177,630 - Filed: 2014-02-11 - Published: 2014-10-02 - Granted: 2016-12-13 - Earliest claimed: 2012-05-14 - Assignees: HeartFlow, Inc. - Applicants: HeartFlow, Inc. - Inventors: Gregory R. Hart; John H. Stevens - Web page: https://patentgrep.com/patent/US9517040B2 ## CPC - A61B 34/10: Computer-aided planning, simulation or modelling of surgical operations - A61B 5/02007: {Evaluating blood vessel condition, e.g. elasticity, compliance} - A61B 5/021: Measuring pressure in heart or blood vessels - A61B 5/026: Measuring blood flow {(A61B3/1233, A61B3/1241 take precedence)} - A61B 5/0263: {using NMR} - A61B 5/7275: {Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor} - A61B 5/7278: {Artificial waveform generation or derivation, e.g. synthesizing signals from measured signals} - A61B 5/7425: {Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image} - A61B 5/7445: {Display arrangements, e.g. multiple display units} - A61B 5/748: {Selection of a region of interest, e.g. using a graphics tablet} - A61B 6/032: {Transmission computed tomography [CT]} - A61B 6/466: {adapted to display 3D data} - A61B 6/504: {for diagnosis of blood vessels, e.g. by angiography} - A61B 6/5217: {extracting a diagnostic or physiological parameter from medical diagnostic data} - A61B 8/06: Measuring blood flow - G06F 3/017: {Gesture based interaction, e.g. based on a set of recognized hand gestures (interaction based on gestures traced on a digitiser G06F3/04883)} - G06F 3/04815: Interaction with a metaphor-based environment or interaction object displayed as three-dimensional [3D], e.g. changing the user viewpoint with respect to the environment or object - G06F 3/0486: Drag-and-drop - G06F 3/0488: using a touch-screen or digitiser, e.g. input of commands through traced gestures - G06F 30/20: Design optimisation, verification or simulation (optimisation, verification or simulation of circuit designs G06F30/30) - G06T 15/00: Three-dimensional [3D] image rendering - G06T 17/00: Three-dimensional [3D] modelling for computer graphics - G06T 19/20: Editing of three-dimensional [3D] images, e.g. changing shapes or colours, aligning objects or positioning parts - G16B 5/00: ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks - G16H 30/20: for handling medical images, e.g. DICOM, HL7 or PACS - G16H 50/50: for simulation or modelling of medical disorders - A61B 5/022: by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers - A61B 6/03: Computed tomography [CT] - A61B 2034/104: {Modelling the effect of the tool, e.g. the effect of an implanted prosthesis or for predicting the effect of ablation or burring} - A61B 2576/023: for the heart - G06T 2200/04: involving 3D image data - G06T 2200/24: involving graphical user interfaces [GUIs] - G06T 2210/41: Medical - G06T 2219/2016: Rotation, translation, scaling - Y02A 90/10: Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N) - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL - G16B: BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA - Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE ## Abstract Embodiments include a system for providing blood flow information for a patient. The system may include at least one computer system including a touchscreen. The at least one computer system may be configured to display, on the touchscreen, a three-dimensional model representing at least a portion of an anatomical structure of the patient based on patient-specific data. The at least one computer system may also be configured to receive a first input relating to a first location on the touchscreen indicated by at least one pointing object controlled by a user, and the first location on the touchscreen may indicate a first location on the displayed three-dimensional model. The at least one computer system may be further configured to display first information on the touchscreen, and the first information may indicate a blood flow characteristic at the first location. ## Claims ### Claim 1 A method for providing patient-specific blood flow information using at least a computer system, the method comprising: receiving over an electronic network, at the computer system, patient-specific anatomical data; generating, based on the received patient-specific anatomical data, a geometric model representing at least a portion of an anatomical structure of a patient, and a reduced-order model of the portion of the anatomical structure; transmitting over the electronic network one or both of the geometric model and the reduced-order model to a portable computer including a touchscreen; receiving over the electronic network, at the computer system, a user intervention input entered by a user on the touchscreen indicating a potential treatment of the anatomical structure that initiates a modification of the reduced-order model; calculating, at the computer system, at least one blood flow characteristic based on the received user intervention input and the modification of the reduced-order model; and transmitting over the electronic network the calculated at least one blood flow characteristic to the portable computer. ### Claim 2 (depends on 1) The method of claim 1, wherein the geometric model is a three-dimensional model. ### Claim 3 (depends on 1) The method of claim 1, wherein the patient-specific anatomical data includes imaging data of at least a portion of an anatomical structure of a patient. ### Claim 4 (depends on 3) The method of claim 3, wherein the anatomical structure includes at least a portion of an aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta. ### Claim 5 (depends on 3) The method of claim 3, wherein the anatomical structure includes at least one of a portion of a plurality of arteries in the patient's heart, neck, head, thorax, abdomen, arms, or legs. ### Claim 6 (depends on 1) The method of claim 1, wherein the modification of the reduced-order model is initiated on the portable computer. ### Claim 7 (depends on 1) The method of claim 1, wherein the modification of the reduced-order model is initiated on the computer system. ### Claim 8 (depends on 1) The method of claim 1, wherein the modification corresponds to placement of a stent. ### Claim 9 (depends on 1) The method of claim 1, wherein the modification corresponds to a formation of a bypass. ### Claim 10 (depends on 1) The method of claim 1, wherein the electronic network is chosen from a wired and a wireless network. ### Claim 11 A system for providing patient-specific blood flow information for a patient, the system comprising at least: a computer system including a processor configured to: receive over an electronic network patient-specific data anatomical data; generate, based on the received patient-specific anatomical data, a geometric model representing at least a portion of an anatomical structure of a patient, and a reduced-order model of the portion of the anatomical structure; transmit over the electronic network one or both of the geometric model and the reduced-order model to a portable computer including a touchscreen; receive over the electronic network a user intervention input entered by a user on the touchscreen indicating a potential treatment of the anatomical structure that initiates a modification of the reduced-order model; calculate at least one blood flow characteristic based on the received user intervention input and the modification of the reduced-order model; and transmit over the electronic network the calculated at least one blood flow characteristic to the portable computer. ### Claim 12 (depends on 11) The system of claim 11, wherein the geometric model is a three-dimensional model. ### Claim 13 (depends on 11) The system of claim 11, wherein the patient-specific anatomical data includes imaging data of at least a portion of an anatomical structure of a patient. ### Claim 14 (depends on 13) The system of claim 13, wherein the anatomical structure includes at least a portion of an aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta. ### Claim 15 (depends on 13) The system of claim 13, wherein the anatomical structure includes at least one of a portion of a plurality of arteries in the patient's heart, neck, head, thorax, abdomen, arms, or legs. ### Claim 16 (depends on 11) The system of claim 11, wherein the modification of the reduced-order model is initiated on the portable computer. ### Claim 17 (depends on 11) The system of claim 11, wherein the modification of the reduced-order model is initiated on the computer system. ### Claim 18 (depends on 11) The system of claim 11, wherein the modification corresponds to placement of a stent. ### Claim 19 (depends on 11) The system of claim 11, wherein the modification corresponds to a formation of a bypass. ### Claim 20 (depends on 11) The system of claim 11, wherein the electronic network is chosen from a wired and a wireless network. ### Claim 21 A non-transitory computer readable medium for use on at least a computer system containing computer-executable programming instructions for providing patient-specific blood flow information, the instructions being executable by the computer system for: receiving over an electronic network, at the computer system, patient-specific anatomical data; generating, based on the received patient-specific anatomical data, a geometric model representing at least a portion of an anatomical structure of a patient, and a reduced-order model of the portion of the anatomical structure; transmitting over the electronic network one or both of the geometric model and the reduced-order model to a portable computer including a touchscreen; receiving over the electronic network, at the computer system, a user intervention input entered by a user on the touchscreen indicating a potential treatment of the anatomical structure that initiates a modification of the reduced-order model; calculating at least one blood flow characteristic based on the received user intervention input and the modification of the reduced-order model; and transmitting the calculated at least one blood flow characteristic to the portable computer. ### Claim 22 (depends on 21) The non-transitory computer readable medium of claim 21, wherein the geometric model is a three-dimensional model. ### Claim 23 (depends on 21) The non-transitory computer readable medium of claim 21, wherein the patient-specific anatomical data includes imaging data of at least a portion of an anatomical structure of a patient. ### Claim 24 (depends on 23) The non-transitory computer readable medium of claim 23, wherein the anatomical structure includes at least a portion of an aorta and at least a portion of a plurality of coronary arteries emanating from the portion of the aorta. ### Claim 25 (depends on 23) The non-transitory computer readable medium of claim 23, wherein the anatomical structure includes at least one of a portion of a plurality of arteries in the patient's heart, neck, head, thorax, abdomen, arms, or legs. ### Claim 26 (depends on 21) The non-transitory computer readable medium of claim 21, wherein the modification of the reduced-order model is initiated on the portable computer. ### Claim 27 (depends on 21) The non-transitory computer readable medium of claim 21, wherein the modification of the reduced-order model is initiated on the computer system. ### Claim 28 (depends on 21) The non-transitory computer readable medium of claim 21, wherein the modification corresponds to placement of a stent. ### Claim 29 (depends on 21) The non-transitory computer readable medium of claim 21, wherein the modification corresponds to a formation of a bypass. ### Claim 30 (depends on 21) The non-transitory computer readable medium of claim 21, wherein the electronic network is chosen from a wired and a wireless network.