Adjuvant for vaccines, vaccines that comprise said adjuvant and uses thereof
AssigneesConsejo Nacional De Investigaciones Cientificas Y Tecnicas, Inis Biotech LLC
InventorsMirta L. Coria, Karina A. Pasquevich, Andres E. Ibanez, Guillermo H. Giambartolomei, Juliana Cassataro, Maria Victoria Delpino
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Abstract
Adjuvant for vaccines that comprises a non-lipidated bacterial outer-membrane polypeptide (Omp), in which the bacteria may be of those of Brucella genus. The adjuvant may be a modified polypeptide or may be, for example, the Omp19S polypeptide or the Omp16S polypeptide, parts or mixtures of the two. In a preferred embodiment, the adjuvant is the non-lipidated polypeptide included in SEQ ID No: 1, or parts thereof. In a further preferred embodiment, the adjuvant is the non-lipidated polypeptide included in SEQ ID No: 2 or parts thereof.
Claims3
A composition comprising a non-lipidated bacterial outer-membrane polypeptide (Omp19S) of the Brucella genus as depicted in SEQ ID NO:
- 1 and at least an antigen selected from the group of allergens, viral antigens, bacterial antigens, parasitic antigens, fungal antigens and tumor cell antigens.
Dependencies are inferred from the claim text.