Microphthalmia-associated transcription factor-derived peptide and composition containing same
AssigneesSupadelixir Inc., Knu-Industry Cooperation Foundation
InventorsKyeong-Han Park, Jang-Hee Hahn, Dong-Young Lim
Life of this patent
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Abstract
Provided are small peptide fragments derived from microphthalmia-associated transcription factor (MITF) and a method for preventing or treating melanoma using the same as an active ingredient. Further provided is a method for skin-whitening and/or for inhibiting skin pigmentation, using the peptide fragments as an active ingredient.
Claims5
A peptide inhibiting microphthalmia-associated transcription factor-mediated transcription, as set forth by SEQ ID NO:
- 1 or SEQ ID NO:
- 3.
A method for treating melanoma, comprising administering an effective amount of a peptide selected from the group consisting of the peptide of SEQ ID NO:
- 1, the peptide of SEQ ID NO:
- 2, the peptide of SEQ ID NO:
- 3 and the peptide of SEQ ID NO:
- 4 to a patient suffering from melanoma.
A method for skin-whitening, comprising administering an effective amount of a peptide selected from the group consisting of the peptide of SEQ ID NO:
- 1, the peptide of SEQ ID NO:
- 2, the peptide of SEQ ID NO:
- 3 and the peptide of SEQ ID NO:
- 4 to a subject in need thereof.
A method for inhibiting skin pigmentation, comprising administering an effective amount of a peptide selected from the group consisting of the peptide of SEQ ID NO:
- 1, the peptide of SEQ ID NO:
- 2, the peptide of SEQ ID NO:
- 3 and the peptide of SEQ ID NO:
- 4 to a subject in need thereof.
A method for inhibiting a skin pigmentation induced by exposure to ultraviolet radiation, comprising administering an effective amount of a peptide selected from the group consisting of the peptide of SEQ ID NO:
- 1, the peptide of SEQ ID NO:
- 2, the peptide of SEQ ID NO:
- 3 and the peptide of SEQ ID NO:
- 4 to a subject in need thereof.
Dependencies are inferred from the claim text.