(Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
AssigneeOryzon Genomics, S.A.
InventorsAlberto Ortega Muñoz, Matthew Colin Thor Fyfe, Marc Martinell Pedemonte, María de los Ángeles Estiarte Martínez, Nuria Valls Vidal, Guido Kurz, Julio Cesar Castro Palomino Laria
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Abstract
The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and theft use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection.
Claims14
A compound selected from N1-((trans)-2-phenylcyclopropyl)cyclohexane-1,4-diamine, an optically active stereoisomer thereof, and a salt or solvate thereof.
A pharmaceutical composition comprising a compound selected from N1-((trans)-2-phenylcyclopropyl)cyclohexane-1,4-diamine, an optically active stereoisomer thereof, and a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier.
A compound selected from (trans)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine and a salt or solvate thereof.
A pharmaceutical composition comprising a compound selected from (trans)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine and a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.