# US 9,468,451 B2 · Medical guide wire > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,468,451 B2 - Document ID: US9468451B2 - Status: Granted - Kind: B2 - Application number: 15/042,156 - Filed: 2016-02-12 - Published: 2016-08-25 - Granted: 2016-10-18 - Earliest claimed: 2015-02-24 - Assignees: FMD Co., Ltd. - Applicants: FMD Co., Ltd. - Inventors: Tsuyoshi Terashi; Seiji Shimura - Web page: https://patentgrep.com/patent/US9468451B2 ## CPC - A61B 17/22: Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for - A61M 25/09: Guide wires - A61B 2017/22001: {Angioplasty, e.g. PCTA} - A61B 2017/22044: {with a pointed tip} - A61B 2017/22094: {for crossing total occlusions, i.e. piercing} - A61M 2025/09083: {having a coil around a core} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A distal end portion 2B of the core has a structure of a combined truncated cone 26 formed by connecting truncated cones satisfying a predetermined relational expression. An outer diameter ratio between the maximum outer diameter and the minimum outer diameter of the combined truncated cone 26 is greater than the outer diameter ratio between a large diameter proximal portion and a small diameter distal portion of an inner coil 4, and is greater than the outer diameter ratio between a large diameter proximal portion and a small diameter distal portion of the outer coil. Because of this, the rotation angle of the proximal side is reduced when rotation operation is performed and the torsional moment toward the distal end side is increased. Thus, the perforation performance at the completely occluded lesion can be improved. ## Claims ### Claim 1 A medical guide wire, comprising: a core that has a portion gradually tapered in diameter from a proximal end side to a distal end side; and an outer coil into which a distal end portion of the core is inserted, wherein the distal end side of the outer coil is connected with the distal end side of the distal end portion of the core to form a distal joining section, the proximal end side of the outer coil is connected with the proximal end side of the distal end portion of the core to form an outer coil proximal joining section, the distal end portion of the core is a combined truncated cone formed by longitudinally connecting at least two truncated cones, a longitudinal length of each of the truncated cones is reduced in order from the proximal end side to the distal end side, an outer diameter ratio between a first maximum outer diameter of the proximal end side and a first minimum outer diameter of the distal end side in each of the truncated cones is increased in order from the proximal end side to the distal end side, the outer diameter ratio is a ratio of the first maximum outer diameter of the proximal end side with respect to the first minimum outer diameter of the distal end side, and when a second maximum outer diameter of the combined truncated cone is defined as D0, a second minimum outer diameter of the combined truncated cone is defined as D1, a total length of the combined truncated cone is defined as L, and an outer diameter Dm of the combined truncated cone at a position separated a distance X from a center in a cross section of the maximum outer diameter D0 to the core distal end of the combined truncated cone within a range of 0{D0−(D0−D1)X/L}. ### Claim 2 (depends on 1) The medical guide wire according to claim 1, wherein the outer coil includes a large diameter proximal portion and a small diameter distal portion in order from the proximal end side to the distal end side, and when an outer diameter of the large diameter proximal portion of the outer coil is defined as B1, an outer diameter of the small diameter distal portion of the outer coil is defined as B2, and a third maximum outer diameter of the proximal end side of the truncated cone located at the most distal end side in the combined truncated cone is defined as D2, an outer diameter ratio (D2/D1) between the third maximum outer diameter D2 of the proximal end side and the second minimum outer diameter D1 of the distal end side in the truncated cone located at the most distal end side in the combined truncated cone is greater than an outer diameter ratio (B1/B2) of the outer coil satisfying the following relational expression: {(D2/D1)>(B1/B2)}. ### Claim 3 (depends on 2) The medical guide wire according to claim 2, wherein an inner coil, which includes a large diameter proximal portion and a small diameter distal portion in order from the proximal end side to the distal end side, is provided outside the distal end portion of the core and inside the outer coil, the inner coil having a shorter longitudinal length than the outer coil and being arranged concentrically with the outer coil, the distal end side of the small diameter distal portion of the inner coil is connected with the distal end side of the distal end portion of the core to form the distal joining section, the proximal end side of the large diameter proximal portion of the inner coil is connected with the proximal end side of the distal end portion of the core to form an inner coil proximal joining section, the combined truncated cone is formed by a first truncated cone and a second truncated cone in order from the proximal end side to the distal end side, at least a part of the second truncated cone is arranged in the inner coil, and when a third maximum outer diameter of the proximal end side of the second truncated cone is defined as D2, a third minimum outer diameter of the distal end side of the second truncated cone is defined as D1, an outer diameter of the large diameter proximal portion of the inner coil is defined as A1, and an outer diameter of the small diameter distal portion of the inner coil is defined as A2, an outer diameter ratio (D2/D1) of the second truncated cone is greater than an outer diameter ratio (D0/D2) of the first truncated cone satisfying the following relational expression: {(D2/D1)>(D0/D2)} and the outer diameter ratio (D2/D1) of the second truncated cone, an outer diameter ratio (A1/A2) of the inner coil and an outer diameter ratio (B1/B2) of the outer coil satisfy the following relational expression: (D2/D1)>(A1/A2)>(B1/B2). ### Claim 4 (depends on 3) The medical guide wire according to claim 3, wherein the outer coil and the inner coil include a large constant diameter proximal portion, a tapered middle portion and a small constant diameter distal portion in order from the proximal end side to the distal end side, the tapered middle portion of the outer coil and the tapered middle portion of the inner coil are arranged to be overlapped with each other, the distal end side of the small constant diameter distal portion of the outer coil, the distal end side of the small constant diameter distal portion of the inner coil and the distal end side of the distal end portion of the core are connected with each other to form the distal joining section, the proximal end side of the large constant diameter proximal portion of the outer coil is connected with the proximal end side of the distal end portion of the core to form the outer coil proximal joining section, the proximal end side of the large constant diameter proximal portion of the inner coil is connected with the distal end portion of the core to form the inner coil proximal joining section, and the large constant diameter proximal portion of the outer coil, the large constant diameter proximal portion of the inner coil and the proximal end side of the second truncated cone are integrally connected with each other to form a middle joining section. ### Claim 5 (depends on 3) The medical guide wire according to claim 3, wherein the outer diameter ratio (D2/D1) of the truncated cone located at the most distal end side in the combined truncated cone is 1.50 to 4.20, the outer diameter ratio (A1/A2) of the inner coil is 1.15 to 2.80, and the outer diameter ratio (B1/B2) of the outer coil is 1.10 to 1.80. ### Claim 6 (depends on 4) The medical guide wire according to claim 4, wherein the outer diameter ratio (D2/D1) of the truncated cone located at the most distal end side in the combined truncated cone is 1.50 to 4.20, the outer diameter ratio (A1/A2) of the inner coil is 1.15 to 2.80, and the outer diameter ratio (B1/B2) of the outer coil is 1.10 to 1.80.