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US 9,457,076 B2Granted
Method for producing vaccinal viral strain of a virus of the Reoviridae family
AssigneeLondon School of Hygiene and Tropical Medicine
InventorsPolly Roy, Mark Boyce
Life of this patent
Estimating the term…
Abstract
The invention relates to a method for producing a modified viral strain of a virus which is a member of the Reoviridae family and, in particular, relates to vaccinal viral strains of the Orbivirus genus.
Claims9
An isolated single stranded RNA (ssRNA) derived from the genome of a Bluetongue virus, wherein the ssRNA comprises a mutation which destroys the function of a Blue Tongue viral gene encoding a VP6 protein, wherein the mutation consists of a deletion of a deletion of nucleotides 301-743 of the gene encoding a Blue Tongue virus gene encoding the VP6 protein.
Dependencies are inferred from the claim text.