# US 9,437,003 B2 · Method, apparatus, and system for correcting medical image according to patient's pose variation

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- Number: US 9,437,003 B2
- Document ID: US9437003B2
- Status: Granted
- Kind: B2
- Application number: 13/861,778
- Filed: 2013-04-12
- Published: 2014-04-24
- Granted: 2016-09-06
- Earliest claimed: 2012-10-24
- Assignees: Samsung Electronics Co., Ltd.
- Applicants: Samsung Electronics Co., Ltd.
- Inventors: Dong-ryeol Park; Hyung-joo Kim
- Web page: https://patentgrep.com/patent/US9437003B2

## CPC

- G06T 7/74: {involving reference images or patches}
- G06T 7/33: using feature-based methods
- G06T 2207/10012: Stereo images
- G06T 2207/10068: Endoscopic image
- G06T 2207/10081: Computed x-ray tomography [CT]
- G06T 2207/10088: Magnetic resonance imaging [MRI]
- G06T 2207/30004: Biomedical image processing
- G06T 2207/30204: Marker
- G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL

## Abstract

Provided is a method of correcting a medical image according to a patient's pose variation. The method includes attaching a marker to an object, generating a first non-real-time image and a first real-time image when the object is in a first pose, generating a second real-time image when the object is in a second pose, and correcting the first non-real-time image based on shift information of the marker when the object is changed from the first pose to the second pose.

## Claims

### Claim 1

An image correcting method, comprising:
attaching a marker to an object, and generating a first non-real-time image, of a first image type, and a first real-time image, of a second image type, including the object's anatomical information about a surrounding region including a position of the marker when the object is in a first pose;
generating a second real-time image, of the second image type, of the object about the surrounding region when the object is in a second pose;
obtaining shift information of the marker based on the first real-time image and the second real-time image when the object is changed from the first pose to the second pose;
correcting, in a processor, the first non-real-time image based on the shift information of the marker; and
displaying the corrected first non-real-time image on a monitor;
wherein the obtaining of the shift information of the marker comprises:
determining a point at which a value measured in data included in the first real-time image exceeds a threshold value, and specifying a first pose relationship between the point and the marker;
selecting a point, corresponding to the point determined in the first real-time image, on the second real-time image, and specifying a second pose relationship between the point selected on the second real-time image and the marker; and
calculating a shift direction and a shift amount of the marker when the object is changed from the first pose to the second pose using the first pose relationship and the second pose relationship.

### Claim 2 (depends on 1)

The method of claim 1, wherein the point at which the value exceeds the threshold value is a point selected in a tissue having a fixed position irrespective of the object's pose variation from among tissue in the object's body included in the first or second real-time image, and
wherein the first pose relationship or the second pose relationship is specified by representing positions of the point and a position of the marker on the first or second real-time image with coordinates.

### Claim 3 (depends on 2)

The method of claim 2, wherein the point is a point obtained by segmenting a surface of the tissue having the fixed position in the first or second real-time image into a plurality of pieces and selecting a piece from among the plurality of pieces.

### Claim 4 (depends on 1)

The method of claim 1, further comprising:
generating a third real-time image including the object's anatomical information about the surrounding region by using an imaging apparatus inserted into the object's body when the object is in the second pose;
wherein the first non-real-time image, the first real-time image, and the second real-time image are generated by using an imaging apparatus disposed outside the object's body.

### Claim 5 (depends on 3)

The method of claim 3, further comprising:
detecting a third pose relationship between the imaging apparatus and the marker and overlaying the third real-time image with the corrected first non-real-time image by using the third pose relationship.

### Claim 6 (depends on 1)

The method of claim 1, wherein the marker comprises a portion that is discernible in the first non-real-time image and the first and second real-time images, and is also discernible outside the object.

### Claim 7 (depends on 1)

The method of claim 1, further comprising:
setting a plurality of points in the corrected first non-real-time image and the first non-real-time image;
measuring a distance between corresponding points of the corrected first non-real-time image and the first non-real-time image; and
determining whether the distance is equal to or less than a predetermined error value.

### Claim 8 (depends on 1)

A non-transitory computer-readable recording medium having embodied thereon a program for executing the method of claim 1.

### Claim 9

An image correcting apparatus, comprising:
a first image generating unit configured to generate a first non-real-time image, of a first image type, including an object's anatomical information about a surrounding region including a position of a marker attached to the object when the object is in a first pose;
a second image generating unit configured to generate a first real-time image, of a second image type, including the object's anatomical information about the surrounding region when the object is in the first pose;
a third image generating unit configured to generate a second real-time image, of the second image type, of the object about the surrounding region when the object is in a second pose;
a shift information obtaining unit configured to obtain shift information of the marker based on the first real-time image and the second real-time image when the object is changed from the first pose to the second pose; and
an image correcting unit configured to correct the first non-real-time image based on the shift information of the marker;
wherein the shift information obtaining unit comprises:
a first pose relationship specifying unit configured to determine a point at which a value measured in data included in the first real-time image exceeds a threshold value, and configured to specify a first pose relationship between the point and the marker;
a second pose relationship specifying unit configured to determine a point, corresponding to the point determined by the first real-time image, on the second real-time image, and configured to specify a second pose relationship between the point determined by the second pose relationship specifying unit and the marker; and
a shift amount and shift direction calculating unit configured to calculate a shift direction and a shift amount of the marker when the object is changed from the first pose to the second pose using the first pose relationship and the second pose relationship.

### Claim 10 (depends on 9)

The apparatus of claim 9, wherein the point at which the value exceeds the threshold value is a point that is selected in a tissue having a fixed position irrespective of the object's pose variation from among tissue in the object's body included in the first or second real-time image, and
wherein the first pose relationship or the second pose relationship is a relationship specified by representing positions of the point and the marker on the first or second real-time image with coordinates.

### Claim 11 (depends on 10)

The apparatus of claim 10, wherein the point is a point obtained by segmenting a surface of the tissue having the fixed position on the first or second real-time image into a plurality of pieces and selecting a piece from among the plurality of pieces.

### Claim 12 (depends on 9)

The apparatus of claim 9, further comprising:
a fourth image generating unit configured to generate a third real-time image including the object's anatomical information about the surrounding region by using an imaging apparatus inserted into the object's body when the object is in the second pose;
wherein the first non-real-time image, the first real-time image, and the second real-time image are images generated by using an imaging apparatus disposed outside the object's body.

### Claim 13 (depends on 12)

The apparatus of claim 12, further comprising:
an image overlaying unit configured to specify a third pose relationship between the imaging apparatus and the marker, and configured to overlay the third real-time image with the corrected first non-real-time image by using the third pose relationship.

### Claim 14 (depends on 9)

The apparatus of claim 9, wherein the marker comprises a portion that is discernible in the first non-real-time image and the first and second real-time images, and also is discernible outside the object.

### Claim 15 (depends on 9)

The apparatus of claim 9, wherein the image correcting unit further comprises an evaluation unit configured to set a plurality of points in the corrected first non-real-time image and the first non-real-time image, configured to measure a distance between corresponding points of the corrected first non-real-time image and the first non-real-time image, and configured to determine whether the distance is equal to or less than a predetermined error value.

### Claim 16

An image correcting system, comprising:
at least one imaging apparatus configured to generate a first non-real-time image, of a first image type, and first through third real-time images including anatomical information of an object to which a marker has been attached; and
an image processing apparatus configured to obtain shift information of the marker using the first real-time image, of a second image type, and the second real-time image, of the second image type, of the object generated by the imaging apparatus, and configured to correct the first non-real-time image based on the shift information of the marker;
wherein the image processing apparatus comprises:
a first pose relationship specifying unit configured to determine a point at which a value measured in data included in the first real-time image exceeds a threshold value, and configured to specify a first pose relationship between the point and the marker;
a second pose relationship specifying unit configured to determine a point, corresponding to the point determined by the first real-time image, on the second real-time image, and configured to specify a second pose relationship between the point determined by the second pose relationship specifying unit and the marker; and
a shift amount and shift direction calculating unit configured to calculate a shift direction and a shift amount of the marker when the object is changed from the first pose to the second pose using the first pose relationship and the second pose relationship.
