# US 9,435,725 B2 · Device, a system and a method for measuring permeability, in particular permeability of a fibrin clot

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- Number: US 9,435,725 B2
- Document ID: US9435725B2
- Status: Granted
- Kind: B2
- Application number: 14/133,684
- Filed: 2013-12-19
- Published: 2014-06-26
- Granted: 2016-09-06
- Earliest claimed: 2012-12-21
- Assignees: Akademia Gorniczo-Hutnicza Im. Stanislawa Staszica W Krakowie
- Applicants: Akademia Gorniczo-Hutnicza Im. Stanislawa Staszica W Krakowie
- Inventors: Adam Pilat; Anetta Undas; Michal Zabczyk
- Web page: https://patentgrep.com/patent/US9435725B2

## CPC

- G01N 15/08: Investigating permeability, pore-volume, or surface area of porous materials
- G01N 15/0826: {and measuring fluid flow rate, i.e. permeation rate or pressure change}
- G01N 33/4905: {Determining clotting time of blood (by chemical methods G01N33/86, C12Q1/56)}
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)

## Abstract

A device for measuring permeability of a material sample, the device comprising: an input tank (1) configured to store fluid and to supply the fluid to a sample tank (2) positioned below the input tank (1) and configured to hold the material sample, such as to allow the fluid from the input tank (1) to permeate through the material sample; a receptacle (25) positioned under the sample tank (2) to collect drops of fluid permeated through the material sample; and a device (3) for measuring the mass of the drops collected in the receptacle (25) and coupled with a controlling and monitoring device (11) configured to store data on measured mass and measurement times.

## Claims

### Claim 1

A device for measuring a permeability of a material sample, the device comprising:
an input tank configured to store a fluid and to supply the fluid to a sample tank positioned below the input tank and configured to hold the material sample, such as to allow the fluid from the input tank to permeate through the material sample;
a receptacle positioned under the sample tank to collect drops of the fluid permeated through the material sample; and
a mass measuring device for measuring a mass of the drops collected in the receptacle and coupled with a controlling and monitoring device configured to store data on the measured mass and measurement times; and,
an electromagnet core for producing an electromagnetic force for holding the sample tank at least partially within the electromagnet core.

### Claim 2 (depends on 1)

The device according to claim 1, further comprising:
a pump connected to a hose for supplying the fluid from a feeding tank to the input tank;
wherein the controlling and monitoring device is further configured to control the pump to supply the fluid from the feeding tank to the input tank in an amount corresponding to the mass of the drops collected in the receptacle.

### Claim 3 (depends on 1)

The device according to claim 1, further comprising a distance measuring element positioned under the receptacle and a distance sensor located coaxially with the vertical axis below the distance measuring element.

### Claim 4 (depends on 1)

The device according to claim 1, wherein the receptacle comprises openings in side walls.

### Claim 5 (depends on 1)

The device according to claim 1, wherein the receptacle has a conical shape.

### Claim 6 (depends on 1)

The device according to claim 1, further comprising a sensor of a temperature of an electromagnet winding.

### Claim 7 (depends on 1)

The device according to claim 1, further comprising a sensor of a temperature of the electromagnet core.

### Claim 8 (depends on 1)

The device according to claim 1, wherein the receptacle has a conical shape and comprises a ring made of a ferromagnetic material or a magnet of a vertical polarization.

### Claim 9 (depends on 8)

The device according to claim 8, wherein the receptacle has a permanent magnet located in a bottom part of the receptacle.

### Claim 10 (depends on 8)

The device according to claim 8, further comprising a magnetic field sensor located in a gap between the electromagnet core and the receptacle.

### Claim 11 (depends on 10)

The device according to claim 10, wherein the magnetic field sensor is a Hall sensor.

### Claim 12 (depends on 1)

The device according to claim 1, wherein the controlling and monitoring device comprises a distance sensor connected to a receptacle position locator being connected to a regulator having a first output connected to a data exchange block and a second output connected to a power controller: the power controller having a first output connected to an electromagnet winding and at least one second output connected in a feedback with the regulator.

### Claim 13 (depends on 1)

The device according to claim 1, wherein the controlling and monitoring device comprises a magnetic field sensor connected to a receptacle position locator being connected to a regulator having an output connected to a power controller, the power controller having a first output connected to an electromagnet winding, and at least one second output connected in a feedback with the regulator.

### Claim 14 (depends on 1)

The device according to claim 1, wherein the controlling and monitoring device comprises a temperature detector having inputs connected to a sensor of a temperature of an electromagnet winding, a sensor of a temperature of the electromagnet core and an external temperature sensor.

### Claim 15

A system for measuring a permeability of a material sample, the system comprising:
a permeability measuring device comprising:
an input tank configured to store a fluid and to supply the fluid to a sample tank positioned below the input tank and configured to hold the material sample, such as to allow the fluid from the input tank to permeate through the material sample;
a receptacle positioned under the sample tank to collect drops of the fluid permeated through the material sample; and
a mass measuring device for measuring a mass of the drops collected in the receptacle and coupled with a controlling and monitoring device configured to store data on the measured mass and measurement times; and,
an electromagnet core for producing an electromagnetic force for holding the sample tank at least partially within the electromagnet core; and,
wherein the controlling and monitoring device is connected to a recording and analyzing device configured to record and analyze data in real-time.

### Claim 16 (depends on 15)

The system according to claim 15, wherein the permeability measuring device is located in a climatic chamber.

### Claim 17 (depends on 15)

The system according to claim 15, further comprising an image recording device directed towards the sample and connected to the controlling and monitoring device.

### Claim 18

A method for measuring a permeability of a material, the method comprising the steps of:
providing a permeability measuring device comprising:
an input tank configured to store a fluid and to supply the fluid to a sample tank positioned below the input tank and configured to hold the material sample, such as to allow the fluid from the input tank to permeate through the material sample;
a receptacle positioned under the sample tank to collect drops of the fluid permeated through the material sample;
a mass measuring device for measuring a mass of the drops collected in the receptacle and coupled with a controlling and monitoring device configured to store data on the measured mass and measurement times; and,
an electromagnet core for producing an electromagnetic force for holding the sample tank at least partially within the electromagnet core; and,
analyzing the measured mass and measurement times for individual drops to determine the permeability of the material stored in the sample tank.

### Claim 19 (depends on 18)

The method according to claim 18, further comprising: feeding the input tank with an amount of the fluid providing a constant hydrostatic pressure influencing the measured material in the sample tank by the fluid from the input tank.
