Method of embolization using a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of polyl(vinyl alcohol)
AssigneesAntia Therapeutics S.A., Universite Claude Bernard Lyon 1, Centre National De La Recherche Scientifique
InventorsYves Chevalier, Géraldine Agusti, Coralie Nyffenegger, Eric Doelker, Olivier Jordan, Gert Andersen
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Abstract
A method of embolizing an area of treatment includes providing a composition that includes a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a poly(vinyl alcohol) (PVA) having covalently grafted thereon iodinated benzyl groups comprising from 1 to 4 iodine atoms per benzyl group as the only substituents wherein a grafted repeating unit has formula (I) wherein n is from 1 to 4: and introducing the composition into the area of treatment.
Claims14
A method of embolizing an area of treatment comprising:
- providing a composition that includes a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a poly(vinyl alcohol) (PVA) having covalently grafted thereon iodinated benzyl groups comprising from 1 to 4 iodine atoms per benzyl group as the only substituents wherein a grafted repeating unit has formula (I)
- wherein n is from 1 to 4;
- and
- introducing the composition into the area of treatment.
A method of embolizing a tumor comprising:
- providing a composition that includes a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of poly(vinyl alcohol) consisting of a poly(vinyl alcohol) (PVA) having covalently grafted thereon iodinated benzyl groups comprising from 1 to 4 iodine atoms per benzyl group as the only substituents wherein a grafted repeating unit has formula (I)
- wherein n is from 1 to 4;
- and
- introducing the composition into a tumor so that the composition forms in-situ a cohesive mass in the tumor.
Dependencies are inferred from the claim text.