# US 9,433,801 B2 · Pacemakers and pacemaker leads

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- Number: US 9,433,801 B2
- Document ID: US9433801B2
- Status: Granted
- Kind: B2
- Application number: 13/527,792
- Filed: 2012-06-20
- Published: 2013-05-02
- Granted: 2016-09-06
- Earliest claimed: 2011-10-28
- Assignees: Tsinghua University; Hon Hai Precision Industry Co., Ltd.
- Applicants: Li Qian; Chen Feng; Wen-Mei Zhao; Li Fan; Yu-Quan Wang; Liang Liu
- Inventors: Li Qian; Chen Feng; Wen-Mei Zhao; Li Fan; Yu-Quan Wang; Liang Liu
- Web page: https://patentgrep.com/patent/US9433801B2

## CPC

- A61N 5/1001: {using radiation sources introduced into or applied onto the body; brachytherapy}
- A61N 1/05: for implantation or insertion into the body, e.g. heart electrode (A61N1/06 takes precedence)
- B82Y 5/00: Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
- H01B 1/04: mainly consisting of carbon-silicon compounds, carbon or silicon
- A61N 1/0529: {Electrodes for brain stimulation}
- A61N 1/056: {Transvascular endocardial electrode systems}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- B82Y: SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- H01B: CABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES (selection for magnetic properties H01F1/00; waveguides H01P {; printed circuits H05K})

## Abstract

A pacemaker is provided. The pacemaker includes a pulse generator and an electrode line connecting with the pulse generator. The electrode line includes at least one conductor. The at least one conductor includes at least one carbon nanotube wire having a plurality of radioactive particles therein.

## Claims

### Claim 1

An electrode line comprising:
at least one lead comprising a first conductor, the first conductor comprising at least one twisted carbon nanotube wire having a plurality of radioactive particles therein; wherein the at least one twisted carbon nanotube wire comprises a plurality of carbon nanotubes joined end to end by van der Waals force, and the plurality of carbon nanotubes are helically oriented around an axis of the at least one twisted carbon nanotube wire, the plurality of radioactive particles are filled in interspaces defined between the plurality of carbon nanotubes of the twisted carbon nanotube wire.

### Claim 2 (depends on 1)

The electrode line of claim 1, wherein a half-life of the plurality of radioactive particles is less than 100 days.

### Claim 3 (depends on 2)

The electrode line of claim 2, wherein the half-life of the plurality of radioactive particles is less than 10 days.

### Claim 4 (depends on 1)

The electrode line of claim 1, wherein a material of the plurality of radioactive particles is selected from the group consisting of 32P, 35S, 47Ca, 89Sr, 111Ag, 115Cd, 185W, 198Au, and 199Au.

### Claim 5 (depends on 1)

The electrode line of claim 1, wherein a decay type of the plurality of radioactive particles is β− decay.

### Claim 6 (depends on 1)

The electrode line of claim 1, further comprising a first insulation layer, a shielding layer, a second insulation layer and a second conductor, wherein the second conductor comprises at least one carbon nanotube wire comprising a plurality of radioactive particles therein.

### Claim 7 (depends on 6)

The electrode line of claim 6, wherein the shielding layer is carbon nanotube structure comprising a plurality of radioactive particles therein.

### Claim 8 (depends on 6)

The electrode line of claim 6, wherein the first insulation layer, the shielding layer, the second insulation layer, and the second conductor are located on an outer surface of the first conductor and arranged from inside to outside.

### Claim 9 (depends on 6)

The electrode line of claim 6, wherein the first insulation layer, the second conductor, the second insulation layer, and the shielding layer are located on an outer surface of the first conductor and arranged from inside to outside.

### Claim 10

A pacemaker, comprising:
a pulse generator; and
an electrode line connecting with the pulse generator, the electrode line comprising at least one conductor;
wherein the at least one conductor comprises at least one carbon nanotube wire and a plurality of radioactive particles located in the at least one carbon nanotube wire, the at least one carbon nanotube wire comprises a plurality of carbon nanotubes, each of the plurality of carbon nanotubes defines an inner space, interspaces are defined by adjacent carbon nanotubes, and the plurality of radioactive particles is distributed in the interspaces of the carbon nanotube wire.

### Claim 11 (depends on 10)

The pacemaker of claim 10, wherein the at least one carbon nanotube wire comprises a plurality of carbon nanotubes extending along an axis of the at least one carbon nanotube wire.

### Claim 12 (depends on 10)

The pacemaker of claim 10, wherein the at least one carbon nanotube wire comprises a plurality of carbon nanotubes extending in a spiral along an axis of the at least one carbon nanotube wire.

### Claim 13

An electrode line having at least one lead, the at least one lead comprising:
a first conductor comprising at least one first carbon nanotube wire having a plurality of radioactive particles therein, the plurality of radioactive particles are filled in interspaces defined between adjacent carbon nanotubes of the first carbon nanotube wire;
a second conductor comprising at least one second carbon nanotube wire;
a first insulation layer located between the first conductor and the second conductor and insulating the first conductor from the second conductor;
a sheath, and the first conductor, the second conductor, and the first insulation layer being located in the sheath; and
an electrode located on an outer surface of sheath and electrically connected to the second conductor, and the electrode being capable of sensing a signal from a tissue and conducting the signal to the second conductor.

### Claim 14 (depends on 13)

The electrode line of claim 13, wherein the at least one first carbon nanotube wire comprises a plurality of carbon nanotubes joined end to end by van der Waals attractive force therebetween, and the plurality of carbon nanotubes are oriented around an axis of the at least one first carbon nanotube wire.

### Claim 15 (depends on 13)

The electrode line of claim 13, wherein the at least one second carbon nanotube wire comprises a plurality of carbon nanotubes joined end to end by van der Waals attractive force therebetween, and the plurality of carbon nanotubes are oriented around an axis of the at least one second carbon nanotube wire.
