# US 9,433,728 B2 · Valveless pharmaceutical infusion system > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,433,728 B2 - Document ID: US9433728B2 - Status: Granted - Kind: B2 - Application number: 13/783,213 - Filed: 2013-03-01 - Published: 2014-09-04 - Granted: 2016-09-06 - Earliest claimed: 2013-03-01 - Assignees: Bayer HealthCare LLC - Applicants: Medrad, Inc. - Inventors: Charles Marsh - Web page: https://patentgrep.com/patent/US9433728B2 ## CPC - A61M 5/14232: {Roller pumps} - A61M 5/007: {for contrast media} - A61M 5/1409: {in series, e.g. reconstitution systems with a first substance passing through a container holding a second substance} - A61M 5/1413: {Modular systems comprising interconnecting elements} - A61M 2205/33: Controlling, regulating or measuring - A61M 2205/50: with microprocessors or computers - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A valveless pharmaceutical infusion system for delivery of a pharmaceutical, such as a radiopharmaceutical, is described. The device may include two or more roller pumps, a fluid path set including a confidence, and a measuring device for measuring a property of the pharmaceutical. Methods for delivering a pharmaceutical, such as a radiopharmaceutical, using a valveless pharmaceutical infusion system are also describe. ## Claims ### Claim 1 A device for delivering a pharmaceutical, the device comprising: two or more roller pumps comprising at least a first roller pump and a second roller pump; and a fluid path set wherein a portion of the fluid path set is reversibly received by the two or more roller pumps, the fluid path set comprising: a first tubing section fluidly connecting a pharmaceutical source to a confluence, wherein a flow of fluid through the first tubing section is controlled by the first roller pump; a second tubing section fluidly connecting a source of medical fluid to the confluence, wherein a flow of fluid through the second tubing section is controlled by the second roller pump; a third tubing section fluidly connecting the confluence to an exit port; a fourth tubing section fluidly connecting the third tubing section or a portion thereof to a waste receptacle; and a waste by-pass tubing section fluidly connecting an upstream portion of the fourth tubing section with a downstream portion of the fourth tubing section, wherein a flow of fluid through the waste by-pass tubing section is controlled by the second roller pump. ### Claim 2 (depends on 1) The device of claim 1, further comprising a delivery tubing section for delivering fluid to a patient, wherein the delivery tubing section is reversibly connected to the exit port. ### Claim 3 (depends on 1) The device of claim 1, wherein the two or more roller pumps further comprise a third roller pump configured to control a flow of fluid through the fourth tubing section. ### Claim 4 (depends on 3) The device of claim 3, further comprising a medical fluid by-pass tubing section fluidly connecting an upstream portion of the second tubing section to a downstream portion of the second tubing section. ### Claim 5 (depends on 4) The device of claim 4, wherein a flow of fluid through the medical fluid by-pass tubing section is controlled by the third roller pump. ### Claim 6 (depends on 5) The device of claim 5, wherein operating the third roller pump causes fluid to flow from the source of medical fluid through the medical fluid by-pass tubing section to the confluence, and into the third tubing section to the exit port. ### Claim 7 (depends on 4) The device of claim 4, wherein the medical fluid by-pass tubing section is fluidly connected to the upstream portion of the second tubing section by a first T-joint, and the medical fluid by-pass tubing section is fluidly connected to the downstream portion of the second tubing section by a second T-joint. ### Claim 8 (depends on 4) The device of claim 4, wherein the medical fluid by-pass tubing section is fluidly connected to the confluence. ### Claim 9 (depends on 1) The device of claim 1, wherein a first T-joint connects the third tubing section to the fourth tubing section. ### Claim 10 (depends on 1) The device of claim 1, wherein the waste by-pass tubing section is fluidly connected to the upstream portion of the fourth tubing section by a first T-joint, and the waste by-pass tubing section is fluidly connected to the downstream portion of the fourth tubing section by a second T-joint. ### Claim 11 (depends on 1) The device of claim 1, wherein fluid from the source of medical fluid can flow through the second tubing section, the confluence, the third tubing section, and into the waste receptacle through the waste by-pass tubing section. ### Claim 12 (depends on 1) The device of claim 1, further comprising an activity measuring device disposed between a first portion of the third tubing section and a second portion of the third tubing section. ### Claim 13 (depends on 12) The device of claim 12, wherein the activity measuring device comprises a measurement coil. ### Claim 14 (depends on 12) The device of claim 12, wherein the activity measuring device measures radioactivity. ### Claim 15 (depends on 1) The device of claim 1, further comprising one or more check valves. ### Claim 16 (depends on 1) The device of claim 1, wherein the confluence comprises one or more check valves.