# US 9,433,708 B2 · Intravenous connector having antimicrobial treatment > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,433,708 B2 - Document ID: US9433708B2 - Status: Granted - Kind: B2 - Application number: 14/216,020 - Filed: 2014-03-17 - Published: 2014-09-18 - Granted: 2016-09-06 - Earliest claimed: 2013-03-15 - Applicants: Patrick E. Eddy - Inventors: Patrick E. Eddy - Web page: https://patentgrep.com/patent/US9433708B2 ## CPC - A61L 29/16: Biologically active materials, e.g. therapeutic substances {(A61L29/048 takes precedence)} - A61L 29/06: obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds - A61M 39/26: Valves closing automatically on disconnecting the line and opening on reconnection thereof {(check valves A61M39/24)} - A61L 2300/208: Quaternary ammonium compounds - A61L 2300/404: Biocides, antimicrobial agents, antiseptic agents - A61M 2039/267: {having a sealing sleeve around a tubular or solid stem portion of the connector} - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract An intravenous connector is provided having a valve body having first end configured to receive a syringe for administering medicine to a patient; a spike element having a tapered hollow spike terminating in a tip at a first end and having a second end configured for attaching to an intravenous tube, the spike element secured in the valve body such that the tip is disposed proximate the first end of the valve body and the second end of the spike element is located at a second end of the valve body; and a pliable seal member disposed in the valve body around the tapered hollow spike and exposed at the first end of the valve body. An antimicrobial material comprising a silane quaternary ammonium salt is incorporated on or within the seal member and is coated on the valve body and the spike element. ## Claims ### Claim 1 An intravenous connector comprising: a valve body having an open first end configured to receive a syringe for administering medicine to a patient; and a silicone seal member disposed in said valve body and exposed at the open first end of said valve body configured to receive the syringe, wherein an antimicrobial material is incorporated on or within said silicone seal member and is coated on said valve body, and wherein said antimicrobial material comprises a silane quaternary ammonium salt. ### Claim 2 (depends on 1) The intravenous connector of claim 1, further comprising: a spike element having a tapered hollow spike terminating in a tip at a first end and having a second end configured for attaching to an intravenous tube, said spike element secured in said valve body such that said tip is disposed proximate the first end of said valve body and the second end of said spike element is located at a second end of said valve body opposite the first end of said valve body, wherein said antimicrobial material is coated on said spike element. ### Claim 3 (depends on 1) The intravenous connector of claim 1, wherein said silane quaternary ammonium salt includes an organofunctional silane covalently bonded to said valve body. ### Claim 4 (depends on 1) The intravenous connector of claim 1, wherein said silane quaternary ammonium salt comprises 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride. ### Claim 5 (depends on 1) The intravenous connector of claim 1, wherein said antimicrobial treatment is applied to said valve body as an antimicrobial treatment solution comprising said silane quaternary ammonium salt and isopropyl alcohol. ### Claim 6 (depends on 5) The intravenous connector of claim 5, wherein the antimicrobial treatment solution comprises about 30 percent to about 50 percent by volume of isopropyl alcohol at the time of application to said valve body. ### Claim 7 (depends on 5) The intravenous connector of claim 5, wherein the antimicrobial treatment solution comprises about 50 percent to about 70 percent by volume of the antimicrobial treatment substance at the time of application to said valve body. ### Claim 8 (depends on 1) The intravenous connector of claim 1, wherein said antimicrobial treatment is substantially free from arsenic, silver, tin, heavy metals and polychlorinated phenols. ### Claim 9 (depends on 1) The intravenous connector of claim 1, wherein said antimicrobial treatment is incorporated within said silicone seal member by mixing said antimicrobial treatment into a silicone slurry used to form said silicone seal member. ### Claim 10 An intravenous connector comprising: a valve body having an open first end configured to receive a syringe for administering medicine to a patient, and a second end opposite the first end; and a spike element having a tapered hollow spike terminating in a tip at a first end and having a second end configured for attaching to an intravenous tube, said spike element secured in said valve body such that said tip is disposed proximate the first end of said valve body and the second end of said spike element is located at the second end of said valve body, a pliable seal member disposed in said valve body around said tapered hollow spike and exposed at the open first end of said valve body configured to receive the syringe, wherein an antimicrobial material is incorporated on or within said seal member and is coated on said valve body and said spike element, and wherein said antimicrobial material comprises a silane quaternary ammonium salt. ### Claim 11 (depends on 10) The intravenous connector of claim 10, wherein said silane quaternary ammonium salt includes an organofunctional silane covalently bonded to said valve body and said spike element. ### Claim 12 (depends on 10) The intravenous connector of claim 10, wherein said silane quaternary ammonium salt comprises 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride. ### Claim 13 (depends on 10) The intravenous connector of claim 10, wherein said antimicrobial treatment is applied to said valve body and said spike element as an antimicrobial treatment solution comprising said silane quaternary ammonium salt and isopropyl alcohol. ### Claim 14 (depends on 10) The intravenous connector of claim 10, wherein said antimicrobial treatment is substantially free from arsenic, silver, tin, heavy metals and polychlorinated phenols. ### Claim 15 (depends on 10) The intravenous connector of claim 10, wherein said pliable seal member is a silicone seal member, and said antimicrobial treatment is incorporated within said silicone seal member by mixing said antimicrobial treatment into a silicone slurry used to form said silicone seal member.