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AssigneeIntron Biotechnology, Inc.
InventorsSeong Jun Yoon, Soo Youn Jun, Hyoung Rok Paik, Jee Soo Son, Hye In Jeong, Sang Hyeon Kang
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The present invention relates to a composition comprising the bacteriophage EK88P-1 isolated from the nature and having a broad antibacterial spectrum against E. coli as an active ingredient, and a method for preventing and treating E. coli infections using the said composition. The bacteriophage EK88P-1, the active ingredient of the composition of the present invention, has a broad antibacterial spectrum against E. coli and has the genome characteristically composed of the partial nucleotide sequences represented by SEQ ID NO: 1 to SEQ ID NO: 25, and also characterized by the bacteriophage belonging to the Myoviridae family according to the morphology that is composed of the major structural proteins in the sizes of approximately 49 kDa, 53 kDa, 94 kDa, and 103 kDa.
A method of treating or reducing mortality due to E. coli diarrhoea in a non-human animal subject, the method comprising the step of spraying on the non-human animal subject or administering orally to the non-human animal subject a composition comprising as the active ingredient an effective concentration of the isolated bacteriophage EK88P-1 having the genome composed of nucleotide sequences set forth in SEQ ID NO:
Dependencies are inferred from the claim text.