# US 9,433,637 B2 · Method for inhibiting influenza virus infection

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- Number: US 9,433,637 B2
- Document ID: US9433637B2
- Status: Granted
- Kind: B2
- Application number: 14/299,503
- Filed: 2014-06-09
- Published: 2014-11-27
- Granted: 2016-09-06
- Earliest claimed: 2003-05-16
- Assignees: Kobayashi Pharmaceutical Co., Ltd.
- Applicants: Kobayashi Pharmaceutical Co., Ltd.
- Inventors: Masafumi Koide; Ryutaro Tsuda; Kenji Fujisawa
- Web page: https://patentgrep.com/patent/US9433637B2

## CPC

- A61K 31/732: Pectin
- A61K 31/7052: having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K 31/713: Double-stranded nucleic acids or oligonucleotides
- A61K 31/715: Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 31/04: Antibacterial agents
- A61P 31/12: Antivirals
- A61P 37/08: Antiallergic agents (antiasthmatic agents A61P11/06; ophthalmic antiallergics A61P27/14)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

Disclosed herein is a method for inhibiting neuraminidase activity in influenza virus by presenting to the influenza virus an effective amount of a preparation, wherein the preparation includes a uronic acid-containing polysaccharide and a negatively charged macromolecular DNA.

## Claims

### Claim 1

A method for inhibiting neuraminidase activity of influenza virus comprising application to a surface an effective amount of a preparation to inhibit neuraminidase, wherein the preparation comprises a uronic acid-containing polysaccharide and a negatively charged macromolecular DNA.

### Claim 2 (depends on 1)

The method of claim 1, wherein the preparation is applied to a mucous membrane.

### Claim 3 (depends on 2)

The method of claim 2, wherein the preparation is applied via an inhalant preparation, gargling preparation, or spray preparation.

### Claim 4 (depends on 1)

The method of claim 1, wherein the acid-containing polysaccharide is a pectin.

### Claim 5 (depends on 1)

The method of claim 1, wherein the preparation is applied to skin.