# US 9,433,590 B2 · Materials and methods for improving alcohol metabolism and alleviating the effects of hangovers

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- Number: US 9,433,590 B2
- Document ID: US9433590B2
- Status: Granted
- Kind: B2
- Application number: 14/021,309
- Filed: 2013-09-09
- Published: 2014-01-09
- Granted: 2016-09-06
- Earliest claimed: 2003-11-19
- Assignees: Omega Bio-Phatma (I.P.1) Ltd.
- Applicants: Omega Bio-Pharma (I.P.1) Ltd.
- Inventors: Wen Qin Tang; Francis Chi
- Web page: https://patentgrep.com/patent/US9433590B2

## CPC

- A61K 31/145: having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2) (isothiourea A61K31/155)
- A61K 31/13: Amines {(A61K31/04 takes precedence)}
- A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61P 1/04: for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A61P 1/12: Antidiarrhoeals
- A61P 3/00: Drugs for disorders of the metabolism (of the blood or the extracellular fluid A61P7/00)
- A61P 25/00: Drugs for disorders of the nervous system
- A61P 25/32: Alcohol-abuse
- A61P 39/02: Antidotes
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The subject invention provides materials and methods for improving alcohol metabolism in animals. In a preferred embodiment, the invention provides methods for increasing the ability of people to consume alcohol while reducing hangovers or other effects of intoxication. Specifically exemplified herein is the use of a cysteamine compound to reduce the adverse effects of alcohol consumption. For example, the undesirable and unpleasant symptoms association with hangovers can be reduced through consumption, according to the subject invention, of cysteamine hydrochloride.

## Claims

### Claim 1

A method for increasing acetaldehyde dehydrogenase activity in a person wherein said method comprises orally administering to a person in need of increasing acetaldehyde dehydrogenase activity a pharmaceutical composition comprising, as an active ingredient, an effective amount of a salt of cysteamine.

### Claim 2

A method for increasing alcohol dehydrogenase activity in a person wherein said method comprises administering to a person in need of increasing alcohol dehydrogenase activity a pharmaceutical composition comprising, as an active ingredient, an effective amount of a salt of cysteamine.

### Claim 3 (depends on 1)

The method of claim 1, wherein said salt of cysteamine is cysteamine hydrochloride.

### Claim 4 (depends on 2)

The method of claim 2, wherein said salt of cysteamine is cysteamine hydrochloride.