# US 9,433,578 B2 · Stable bubbles via particle absorption by electrostatic interaction > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,433,578 B2 - Document ID: US9433578B2 - Status: Granted - Kind: B2 - Application number: 13/896,666 - Filed: 2013-05-17 - Published: 2014-11-20 - Granted: 2016-09-06 - Earliest claimed: 2013-05-17 - Assignees: L'oreal - Applicants: L'oreal - Inventors: Vance Bergeron; Jean-Thierry Simonnet; Florence Levy; Aurelie Lafuma; Stephane Santucci - Web page: https://patentgrep.com/patent/US9433578B2 ## CPC - A61K 9/107: Emulsions {; Emulsion preconcentrates; Micelles (composition of emulsions A61K47/00)} - A23L 29/10: containing emulsifiers - A23L 35/10: {Emulsified foodstuffs} - A23P 30/40: Foaming or whipping - A61K 8/0245: {Specific shapes or structures not provided for by any of the groups of A61K8/0241} - A61K 8/025: {Explicitly spheroidal or spherical shape} - A61K 8/0254: {Platelets; Flakes} - A61K 8/04: Dispersions; Emulsions - A61K 8/046: {Aerosols; Foams} - A61K 8/19: containing inorganic ingredients - A61K 8/25: Silicon; Compounds thereof - A61K 8/416: {Quaternary ammonium compounds (A61K8/35 takes precedence)} - C09K 23/002: {Inorganic compounds} - C09K 23/18: Quaternary ammonium compounds - A61K 2800/596: Mixtures of surface active compounds - A61K 2800/805: Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95 - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B) - A23P: SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS - C09K: MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE ## Abstract Disclosed are methods of preparing stable gas-in-solution emulsions by particle adsorption via electrostatic interaction, and stable emulsions prepared by particle adsorption via electrostatic interaction. Compositions and products comprising the emulsions are also disclosed. Emulsions may be stable over an extended period of time at room temperature. ## Claims ### Claim 1 A method for preparing an emulsion, said method comprising mixing a gas-in-solution dispersion and a solution comprising particles, wherein: a. the gas-in-solution dispersion comprises at least one surface active agent in the continuous phase, and a disperse phase comprising gas bubbles; and b. the particle solution comprises particles having an opposite charge than that of the surface active agent. ### Claim 2 (depends on 1) The method according to claim 1, wherein the gas bubbles are chosen from bubbles of air, O2, N2, CO2, N2O, He, and combinations thereof. ### Claim 3 (depends on 1) The method according to claim 1, wherein the at least one surface active agent is chosen from cationic and anionic surface active agents. ### Claim 4 (depends on 3) The method according to claim 3, wherein the at least one cationic surface active agent is chosen from optionally polyoxyalkylenated primary, secondary and tertiary fatty amines, quaternary ammonium salts, and mixtures thereof. ### Claim 5 (depends on 3) The method according to claim 3, wherein the at least one cationic surface active agent is chosen from at least one amphoteric surface active agent that has been pH-adjusted to be cationic. ### Claim 6 (depends on 5) The method according to claim 5, wherein the at least one cationic surface active agent chosen from at least one amphoteric surface active agent that has been pH-adjusted to be cationic is chosen from derivatives of betaine, derivatives of alkylamphoacetate, derivatives of hydroxylsultaines, and mixtures thereof. ### Claim 7 (depends on 3) The method according to claim 3, wherein the at least one anionic surface active agent is chosen from alkyl ether citrates; alkenyl succinates chosen from alkoxylated alkenyl succinates, alkoxylated glucose alkenyl succinates, and alkoxylated methylglucose alkenyl succinates; phosphoric acid fatty esters; alkaline salts of dicetyl and dimyristyl phosphate; alkaline salts of cholesterol sulfate; alkaline salts of cholesterol phosphate; lipoamino acids and their salts; sodium salts of phosphatidic acid; phospholipids; alkylsulfonic derivatives; and mixed esters of glycerol with 1) and 2), wherein 1) and 2) are as follows: 1) at least one fatty acid or fatty alcohol, and 2) at least one carboxylic acid. ### Claim 8 (depends on 1) The method according to claim 1, wherein the gas bubbles have a charge greater than about 40 mV after preparing the gas-in-solution dispersion. ### Claim 9 (depends on 8) The method according to claim 8, wherein the particles have a charge greater than about 20 mV after preparing the particle solution. ### Claim 10 (depends on 1) The method according to claim 1, wherein the particles are chosen from organic and inorganic particles. ### Claim 11 (depends on 10) The method according to claim 10, wherein the particles are surface-modified to provide electrostatic interaction with the surface-active agent. ### Claim 12 (depends on 10) The method according to claim 10, wherein the particles are chosen from nylon particles, PPMA particles, styrene particles, and silica particles. ### Claim 13 (depends on 1) The method according to claim 1, wherein the gas bubble to particle size ratio ranges from about 5 to about 20. ### Claim 14 (depends on 1) The method according to claim 1, wherein the solution comprising particles comprises particles having a contact angle of less than about 90°. ### Claim 15 (depends on 1) The method according to claim 1, wherein the particles are present in the solution in an amount ranging from about 0.2 wt % to about 25 wt %. ### Claim 16 A method for preparing an emulsion, said method comprising the steps of: a. preparing a solution having at least one cationic surface active agent; b. dispersing gas bubbles in the solution to obtain a gas-in-solution dispersion comprising gas bubbles having a cationic charge; c. preparing a solution comprising particles having an anionic charge; and d. mixing the gas-in-solution dispersion comprising gas bubbles having a cationic charge and the solution comprising particles having an anionic charge. ### Claim 17 A method for preparing an emulsion, said method comprising the steps of: a. preparing a solution having at least one anionic surface active agent; b. dispersing gas bubbles in the solution to obtain a gas-in-solution dispersion comprising gas bubbles having an anionic charge; c. preparing a solution comprising particles having a cationic charge; and d. mixing the gas-in-solution dispersion comprising gas bubbles having an anionic charge and the solution comprising particles having a cationic charge. ### Claim 18 A gas-in-solution emulsion comprising gas bubbles comprising a cationic charge at the gas/solution interface, wherein said gas bubbles are encapsulated by anionic particles. ### Claim 19 A gas-in-solution emulsion comprising gas bubbles comprising an anionic charge at the gas/solution interface, wherein said gas bubbles are encapsulated by cationic particles. ### Claim 20 (depends on 18) The gas-in-solution emulsion according to claim 18, wherein the emulsion is stable for at least 6 months at room temperature. ### Claim 21 (depends on 19) The gas-in-solution emulsion according to claim 19, wherein the emulsion is stable for at least 6 months at room temperature.