# US 9,433,570 B2 · Composition for cosmetic, pharmaceutical and dietary applications

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- Number: US 9,433,570 B2
- Document ID: US9433570B2
- Status: Granted
- Kind: B2
- Application number: 14/141,560
- Filed: 2013-12-27
- Published: 2014-05-01
- Granted: 2016-09-06
- Earliest claimed: 2009-06-24
- Assignees: Lipoid GmbH
- Applicants: LIPOID GmbH
- Inventors: Herbert Rebmann
- Web page: https://patentgrep.com/patent/US9433570B2

## CPC

- A61K 8/73: Polysaccharides
- A23B 2/92: Freeze drying
- A23L 33/105: Plant extracts, their artificial duplicates or their derivatives
- A61K 8/553: {Phospholipids, e.g. lecithin}
- A61K 8/60: Sugars; Derivatives thereof
- A61K 8/9741: Pteridophyta [ferns]
- A61K 8/9771: Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
- A61K 8/9789: Magnoliopsida [dicotyledons]
- A61K 8/9794: Liliopsida [monocotyledons]
- A61K 9/06: Ointments; Bases therefor; {Other semi-solid forms, e.g. creams, sticks, gels (composition of ointments, creams or gels A61K47/00)}
- A61K 9/127: Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K 9/19: lyophilised {, i.e. freeze-dried, solutions or dispersions (lyophilised products with subsequent particle size reduction A61K9/14; granules or pellets made by lyphilisation A61K9/1682; solid oral dosage forms made by lyophilisation A61K9/2095; lyophilisation additives A61K47/00)}
- A61K 31/522: having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A61K 31/685: one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A61K 31/716: Glucans
- A61K 36/16: Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
- A61K 36/23: Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K 36/258: Panax (ginseng)
- A61K 36/31: Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K 36/45: Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
- A61K 36/48: Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K 36/5775: {Hibiscus}
- A61K 36/63: Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K 36/77: Sapindaceae (Soapberry family), e.g. lychee or soapberry
- A61K 36/82: Theaceae (Tea family), e.g. camellia
- A61K 36/886: Aloeaceae (Aloe family), e.g. aloe vera
- A61Q 19/00: Preparations for care of the skin
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A23B: PRESERVATION OF FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES; CHEMICAL RIPENING OF FRUIT OR VEGETABLES
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

A composition including 0.5-40 weight % vegetable extract, 30-90 weight % sugar and 0.5-30 weight % phospholipid for cosmetic, pharmaceutical or dietary uses.

## Claims

### Claim 1

A composition, consisting of:
a) 0.5-40 weight % vegetable extract;
b) 30-90 weight % sugar; and
c) 0.5-30 weight % phospholipid including 40-80 weight % of phosphatidylcholine, wherein the composition is in a dry form as a powder or as granules.

### Claim 2 (depends on 1)

The composition according to claim 1, consisting of:
a) 18-35 weight % of the vegetable extract;
b) 40-80 weight % of the sugar; and
c) 1-25 weight % of the phospholipid.

### Claim 3 (depends on 1)

The composition according to claim 1, consisting of:
a) 28-32 weight % of the vegetable extract;
b) 60-70 weight % of the sugar; and
c) 2-8 weight % of the phospholipid.

### Claim 4 (depends on 1)

The composition according to claim 1, consisting of:
a) 30 weight % of the vegetable extract;
b) 67 weight % of the sugar; and
c) 3 weight % of the phospholipid.

### Claim 5 (depends on 1)

The composition according to claim 1, wherein the sugar is selected from the group consisting of mannit, glucose, trehalose, sucrose, lactose, fructose, mannose, ribose, galactose, rhamnose, lactulose, maltose and raffinose.

### Claim 6 (depends on 1)

The composition according to claim 1, wherein the sugar is selected from the group consisting of mannit, glucose, trehalose and saccharose.

### Claim 7 (depends on 1)

The composition according to claim 1, wherein the dry form is a lyophilisate.

### Claim 8 (depends on 7)

The composition according to claim 7, wherein the composition spontaneously forms liposomes when redispersing.

### Claim 9 (depends on 1)

The composition according to claim 1, wherein the vegetable extract is selected from the group consisting of Aloe, Rooibos, Guarana, white tea, green tea, black tea, Hibiskus, Nettle, Rorippa amphibia, water cress, horse tail, field horsetail, chamomile, Centella asiatica, Gingko, Ginseng, Cranberry, olive and pomegranate or mixtures thereof.

### Claim 10 (depends on 1)

A method for the production of a composition according to claim 1, the method comprising:
a) dispersing and homogenizing the vegetable extract, the sugar and the phospholipid in water to form a dispersion;
b) sterile filtering the dispersion and subsequently drying the dispersion at −30° C. to +45° C. to form a dried product; and
c) grinding the dried product to a grain size with an orifice diameter of 0.5-1.5 mm.

### Claim 11 (depends on 1)

The composition according to claim 1 as a cosmetic, dietary or pharmaceutical formulation.

### Claim 12 (depends on 1)

The composition according to claim 1, wherein the sugar is selected from the group consisting of dextrin and maltodextrin.

### Claim 13 (depends on 2)

The composition of claim 2, wherein the sugar is a maltodextrin.

### Claim 14 (depends on 3)

The composition of claim 3, wherein the sugar is a maltodextrin.

### Claim 15 (depends on 1)

The composition according to claim 1, wherein the phospholipid is a hydrogenated phospholipid.

### Claim 16 (depends on 13)

The composition according to claim 13, wherein the phospholipid is a hydrogenated phospholipid.

### Claim 17 (depends on 14)

The composition according to claim 14, wherein the phospholipid is a hydrogenated phospholipid.