# US 9,433,553 B2 · Device and method for prevention and treatment of deep venous thrombosis

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- Number: US 9,433,553 B2
- Document ID: US9433553B2
- Status: Granted
- Kind: B2
- Application number: 14/601,106
- Filed: 2015-01-20
- Published: 2015-07-16
- Granted: 2016-09-06
- Earliest claimed: 2001-09-21
- Assignees: Fred Herz Patents, LLC
- Applicants: Fred Herz Patents LLC
- Inventors: Frederick S. M. Herz; Frederick A. Reichle
- Web page: https://patentgrep.com/patent/US9433553B2

## CPC

- A61H 9/0007: {Pulsating}
- A61B 17/135: inflatable
- A61H 9/0078: {with intermittent or alternately inflated bladders or cuffs (mattresses for preventing bed-sores with alternated pressurized chambers A61G7/05776)}
- A61M 5/142: Pressure infusion, e.g. using pumps
- A61H 2205/12: Feet
- A61M 2202/07: Proteins
- A61H: PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY (electrotherapy, magnetotherapy, radiation therapy or ultrasound therapy A61N)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

In order to inhibit thrombotic processes locally rather than systemically, higher levels of antithrombotic drugs in the deep veins of the legs than in the systemic circulation are obtained using devices and methods that provide venous cannulation in the dorsum of the foot of a patient while applying pressure to the foot proximal to the venous cannulation, potentially as far up the leg as the knee, in an amount sufficient to compress the superficial veins and divert the venous drainage in the deep venous system into the venous plexus.

## Claims

### Claim 1

A method of delivering an antithrombotic drug into deep veins of a leg of a patient, comprising the steps of:
providing venous cannulation in a dorsum of a foot of the patient for application of said antithrombotic drug into superficial veins of the foot of the patient;
adjusting at least one adjustable pressure strap on the foot of the patient so as provide a compressive force sufficient to compress the superficial veins of the foot of the patient, the adjustable pressure strap having an elastic gauge scale for use in adjusting the strap until a uniform pressure is applied to the foot of the patient sufficient to compress superficial veins of the foot of the patient; and
injecting said antithrombotic drug into the superficial veins of the foot of the patient or via alternating web spaces of the foot of the patient while the pressure is applied to the foot of the patient whereby said antithrombotic drug is shunted to deep veins of the leg of the patient via the compressed superficial veins of the foot of the patient.

### Claim 2 (depends on 1)

A method as in claim 1, wherein the antithrombotic drug comprises an anti-coagulant.

### Claim 3 (depends on 2)

A method as in claim 2, wherein the anti-coagulant is unfractionated heparin or low molecular weight heparin.

### Claim 4 (depends on 1)

A method as in claim 1, wherein the step of providing venous cannulation comprises accessing the superficial veins of the foot of the patient via a window of an inflatable pedal venous stocking configured to provide dorsal pedal access for the venous cannulation.