# US 9,433,354 B2 · Devices for modulation of retinal stimulation and/or retinal signal processing and methods of use thereof

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- Number: US 9,433,354 B2
- Document ID: US9433354B2
- Status: Granted
- Kind: B2
- Application number: 14/848,766
- Filed: 2015-09-09
- Published: 2015-12-31
- Granted: 2016-09-06
- Earliest claimed: 2011-07-05
- Applicants: Deborah Zelinsky
- Inventors: Deborah Zelinsky
- Web page: https://patentgrep.com/patent/US9433354B2

## CPC

- A61B 5/0082: {adapted for particular medical purposes}
- A61B 5/0042: {for the brain}
- A61B 5/055: involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
- A61B 5/24: Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B 5/4064: {Evaluating the brain (for intracranial pressure A61B5/031; for cerebral blood gases A61B5/14553; using EEG A61B5/369)}
- A61B 5/4082: {Diagnosing or monitoring movement diseases, e.g. Parkinson, Huntington or Tourette}
- A61B 5/4088: {Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia}
- A61B 5/4094: {Diagnosing or monitoring seizure diseases, e.g. epilepsy}
- A61B 5/7246: {using correlation, e.g. template matching or determination of similarity}
- A61N 5/0622: {Optical stimulation for exciting neural tissue}
- A61N 2005/0635: {characterised by the body area to be irradiated}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

The present disclosure provides devices and methods for the modulation of retinal stimulation and/or retinal signal processing. Such methods may be useful for the diagnosis, treatment or prevention of a disease or disorder. The disclosed methods may comprise visual intervention by using lenses, prisms, mirrors, and/or filters (e.g., occluders) to alter the amount and/or direction of light on to the retina.

## Claims

### Claim 1

A method for the treatment of a disease or disorder, said method comprising:
a) diagnosing a subject as having a disease or disorder amenable to treatment by activation of non-visual retinal pathways; and
b) modulating non-visual retinal pathways in the subject's eye using one or more frequencies of light directed to one or more discrete areas of the subject's retina to treat the disease or disorder.

### Claim 2 (depends on 1)

The method of claim 1, wherein the modulation of non-visual retinal pathways is conducted at a selected time in a home setting.

### Claim 3 (depends on 1)

The method of claim 1, wherein the modulation of non-visual retinal pathways is conducted at a selected time in an institutional setting.

### Claim 4 (depends on 1)

The method of claim 1, wherein modulating includes stimulating or inhibiting.
