Method of constructing at least one three-dimensional image

A method of constructing at least one 3 dimensional image from a plurality of data, the method comprising:

• extracting and labeling vessel information from at least one image, wherein the vessel information is represented by a plurality of gray scale value points;
• partitioning the at least one image into a plurality of portions;
• determining a plurality of gray scale value points in each portion of the plurality of portions;
• calculating the number of gray scale value points for each portion of the plurality of portions;
• comparing each of the number of gray scale value points for each portion of the plurality of portions with a threshold value, wherein:
• when the number of gray scale value points for a given portion of the plurality of portions is less than the threshold value, determining a center of gravity for the given portion of the plurality of portions based at least in part on the plurality of gray scale value points in the given portion, and
• when the number of gray scale value points for a given portion of the plurality of portions is larger than or equal to the threshold value, the given portion is further divided into a plurality of portions and the determining, calculating and comparing steps are repeated for each portion of the plurality of portions;
• and
• connecting at least a subset of the centers of gravity of each of the plurality of portions to extract a vessel centerline.