System and method for eluting and testing substance from exhaled aerosol sample
AssigneeSensa Bues AB
InventorOlof Beck
Life of this patent
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Abstract
A method recovering one or more nonvolatile compounds from an exhaled aerosol collected on an electrostatic filter membrane (205) comprises eluting the nonvolatile compounds from the filter with a polar solvent and collecting the eluate. The method is useful for processing samples collected from a portable breath analysis device comprising a sampling filter membrane for analysis.
Claims18
A method for recovery of non-volatile compounds from an electrostatic filter membrane, wherein said electrostatic filter membrane is fitted in a housing comprising at least one inlet and at least one outlet and wherein said housing is part of a sampling system for exhaled breath, the method comprising:
- providing said electrostatic filter membrane containing an exhaled aerosol comprising a nonvolatile compound;
- washing said electrostatic filter membrane with a polar organic solvent to form an eluate;
- collecting said eluate comprising said nonvolatile compound;
- and
- pouring said solvent in one of said inlet or outlet and collecting said eluate through the other of said inlet or outlet.
A method for recovery of non-volatile compounds from an electrostatic filter membrane, comprising:
- providing said electrostatic filter membrane containing an exhaled aerosol comprising a nonvolatile compound, wherein said electrostatic filter membrane is fitted in a housing comprising at least one inlet and at least one outlet;
- washing said electrostatic filter membrane with a polar organic solvent while fitted in said housing to form an eluate, the washing including passing the solvent though the housing from one of the inlet or outlet to the other of the inlet or outlet;
- and
- collecting said eluate comprising said nonvolatile compound from the other of said inlet or outlet.
A method for recovery of non-volatile compounds from an electrostatic filter membrane, comprising:
- providing said electrostatic filter membrane containing an exhaled aerosol comprising a nonvolatile compound;
- washing said electrostatic filter membrane with a polar organic solvent to form an eluate;
- collecting said eluate comprising said nonvolatile compound;
- wherein said electrostatic filter membrane is fitted in a housing comprising at least one inlet and at least one outlet, and said washing includes pouring said solvent in one of said inlet or outlet and collecting said eluate through the other;
- and
- evaporating said eluate at least partially.
Dependencies are inferred from the claim text.