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US 9,428,571 B2Granted
Antibodies and processes for preparing the same
AssigneeTaiga Biotechnologies, Inc.
InventorsYosef Refaeli, Brian Turner
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Abstract
Provided herein are various processes for the improved production of antibody producing organisms, antibody producing tissues, antibody producing cells and antibodies. In certain embodiments, provided herein are methods for rapidly producing antibody producing organisms, tissues, cells and antibodies derived from humans, organisms, plants or cells that are genetically altered to over-express certain proteins.
Claims22
A fusion peptide, comprising:
- (a) a protein transduction domain sequence, wherein the protein transduction domain sequence is an HIV Tat protein transduction domain sequence or a viral protein R (vpr) protein transduction domain sequence;
- (b) a full-length MYC sequence having a biological activity of MYC;
- and
- (c) at least two protein tags, wherein the protein tags comprise a 6-histidine tag and a V5 epitope tag;
- wherein the fusion peptide is able to enter the nucleus of a cell.
2 more elements
A composition comprising:
- (a) a fusion peptide, comprising:
- (i) a protein transduction domain sequence, wherein the protein transduction domain sequence is an HIV Tat protein transduction domain sequence or a viral protein R (vpr) protein transduction domain sequence;
- (ii) a full-length MYC sequence having a biological activity of MYC;
- and
- (iii) at least two protein tags, wherein the protein tags comprise a 6-histidine tag and a V5 epitope tag:
- wherein the fusion peptide is able to enter the nucleus of a cell;
- and
- (b) one or more pharmaceutically acceptable excipients.
5 more elements
Dependencies are inferred from the claim text.