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AssigneeKorea Research Institute of Bioscience and Biotechnology
InventorsJae Wha Kim, Kyung Seop Ahn, Ho Bum Kang, Sei Ryang Oh, Jae Jong Go, Joo Heon Kim, Jang Mi Sun, Jae Sung Song, Hyun Woo Oh, Da Jung Ji
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The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
A method for treating atopy comprising administering to a subject in need thereof a pharmaceutically effective amount of a purified compound of Formula 1:
Dependencies are inferred from the claim text.