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US 9,428,515 B2Granted
Benzimidazole derivatives
AssigneeBoehringer Ingelheim International GmbH
InventorHarald Engelhardt
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Abstract
The present invention encompasses compounds of the general formula I wherein the groups A, R1 to R2 and X have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.
Claims12
A compound of formula I
- wherein,
- A is
- R1 is
- R2 is selected from the group consisting of —CH2-phenyl, —CH(CH3)-phenyl, —CH2—CH2—O—CH3 and —CH(CH3)—CH2—O—CH3,
- R3 is —C1-3 alkyl;
- R4 is —C1-3 alkyl;
- R5 is —C1-3 alkyl;
- or R4 and R5 taken together form a —C3 cycloalkyl;
- R6 is —C1-3 alkyl;
- R7 is —C1-3 alkyl;
- R8 is —C1-3 alkyl;
- R9 is —C1-3 alkyl;
- R10 is —C1-3 alkyl;
- and
- X is —CH═;
- or a salt thereof.
13 more elements
Dependencies are inferred from the claim text.