Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith

A compound of formula (I):

• and pharmaceutically acceptable salts, tautomers, stereoisomers, enantiomers, and isotopologues thereof,
• wherein:
• R1 is substituted or unsubstituted C1-8 alkyl, substituted or unsubstituted C3-8 cycloalkyl, or substituted or unsubstituted non-aromatic heterocyclyl;
• R2 is substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R3 is substituted or unsubstituted heterocyclyl or substituted or unsubstituted aryl, and
• L is NH or O;
• provided
• R3 is not pyridyl when L is NH or when R2 is pyrazolyl;
• and
• the compound is not
• N-methyl-N-[trans-3-[[5-(1-methyl-1H-pyrazol-4-yl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]cyclobutyl]-2-propenamide;
• or
• N-methyl-N-[trans-3-[[5-(1-methyl-1H-pyrazol-3-yl)-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]cyclobutyl]-2-propenamide.