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US 9,428,493 B2Granted
Schweinfurthin analogues
AssigneeUniversity of Iowa Research Foundation
InventorsJohn Kodet, Jeffrey D. Neighbors, David F. Wiemer
Life of this patent
Estimating the term…
Abstract
The invention provides a compound of formula (I): wherein R1-R5 have any of the values defined in the specification. The compounds are useful for the treatment of cancer and other diseases.
Claims14
A compound of formula (I):
- wherein:
- R1 is H or (C1-C6)alkyl;
- R2 is H, (C1-C15)alkyl, (C2-C15)alkenyl, aryl, or heteroaryl, wherein any aryl or heteroaryl is optionally substituted with one or more groups independently selected from halo, nitro, trifluoromethyl, trifluoromethoxy, nitro, cyano, (C1-C6)alkyl, (C3-C6)cycloalkyl, (C3-C6)cycloalkyl(C1-C6)alkyl, (C1-C6)alkoxy, (C1-C6)alkanoyl, (C1-C6)alkoxycarbonyl, and (C2-C6)alkanoyloxy;
- R3 is H, (C1-C15)alkyl, or (C2-C15)alkenyl;
- R4 is H or (C1-C6)alkyl;
- and
- R5 is H or (C1-C6)alkyl;
- or a salt thereof;
- provided R2 is not (C2-C5)alkenyl;
- and
- provided the compound of formula (I) is not:
8 more elements
A compound selected from:
- or a salt thereof.
A compound selected from:
- or a salt thereof.
Dependencies are inferred from the claim text.