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US 9,428,459 B2Granted
Difluoromethyl-nicotinic- tetrahydronaphtyl carboxamides
AssigneeBayer CropScience AG
InventorsSimon Maechling, Alexander Sudau, Ulrike Wachendorff-Neumann, Christophe Dubost, David Bernier, Lionel Carles, Jean-Pierre Vors, Stephane Brunet, Helene Lachaise
Life of this patent
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Abstract
The present invention relates to novel difluoromethyl-nicotinic indanyl carboxamide compounds, to processes for preparing the carboxamide compounds, to compositions comprising the carboxamide compounds, and to the use thereof as biologically actives, especially for control of harmful microorganisms in crop protection and in the protection of materials.
Claims16
Difluoromethyl-nicotinic tetrahydronaphtyl carboxamide of formula (I)
- in which
- X1 represents halogen;
- cyano;
- C1-C6-alkyl, C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms;
- C3-C7-cycloalkyl, C3-C7-halocycloalkyl having 1 to 9 identical or different halogen atoms;
- n represents 0, 1, 2 or 3;
- T represents an oxygen or sulfur atom;
- Q represents hydrogen, optionally substituted C1-C6-alkylsulfonyl;
- optionally substituted C1-C4-alkoxy-C1-C4-alkyl, optionally substituted C1-C4-haloalkylsulfonyl;
- Ra represents hydrogen, halogen, nitro, cyano, C1-C12-alkyl;
- C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms;
- C1-C6-alkoxy;
- C1-C6-haloalkoxy having 1 to 9 identical or different halogen atoms;
- C1-C6-alkylsulfanyl;
- C1-C6-haloalkylsulfanyl having 1 to 9 identical or different halogen atoms;
- C1-C6-alkylsulfonyl;
- C1-C6-haloalkylsulfonyl having 1 to 9 identical or different halogen atoms;
- C2-C12-alkenyl;
- C2-C12-alkynyl;
- C3-C7-cycloalkyl;
- phenyl;
- tri(C1-C8)alkylsilyl;
- tri(C1-C8)alkylsilyl-C1-C8-alkyl;
- R1, R2, R3, R4, R5, R6, R7 and R8 independently of one another represent hydrogen;
- halogen;
- cyano;
- C1-C16-alkyl;
- C1-C16-haloalkyl having 1 to 9 identical or different halogen atoms;
- C3-C8-cycloalkyl;
- (C3-C8-cycloalkyl)-C1-C8-alkyl;
- (C3-C8-cycloalkyl)-C3-C8-cycloalkyl;
- C2-C8-alkenyl;
- C2-C8-alkynyl;
- C2-C8-alkenyl-C1-C16-alkyl;
- C2-C8-alkynyl-C1-C16-alkyl;
- C1-C16-alkoxy;
- C3-C8-cycloalkyloxy;
- (C3-C8-cycloalkyl)-C1-C8-alkyloxy;
- C1-C8-alkylsulfanyl;
- C3-C8-cycloalkylsulfanyl;
- (C3-C8-cycloalkyl)-C1-C8-alkylsulfanyl;
- C2-C8-alkenyloxy;
- C3-C8-alkynyloxy;
- aryl-C1-C8-alkyloxy which is optionally substituted by up to 6 identical or different groups Rb;
- aryl-C1-C8-alkylsulfanyl which is optionally substituted by up to 6 identical or different groups Rb;
- aryloxy which is optionally substituted by up to 6 identical or different groups Rb;
- arylsulfanyl which is optionally substituted by up to 6 identical or different groups Rb;
- (C3-C8-cycloalkyl)-C2-C8-alkenyl;
- (C3-C8-cycloalkyl)-C2-C8-alkynyl;
- optionally substituted tri(C1-C8)alkylsilyl;
- tri(C1-C8)alkylsilyl-C1-C8-alkyl;
- aryl-C1-C8-alkyl which is optionally substituted by up to 6 identical or different groups Rb;
- aryl-C2-C8-alkenyl which is optionally substituted by up to 6 identical or different groups Rb;
- aryl-C2-C8-alkynyl which is optionally substituted by up to 6 identical or different groups Rb;
- C1-C8-alkylamino;
- di-C1-C8-alkylamino;
- arylamino which is optionally substituted by up to 6 identical or different groups Rb;
- C1-C8-alkylcarbonyl C1-C8-alkylcarbonyloxy;
- C1-C8-alkylcarbonylamino;
- C1-C8-alkoxycarbonyl;
- C1-C8-alkyloxycarbonyloxy;
- C1-C8-alkylcarbamoyl;
- di-C1-C8-alkylcarbamoyl;
- C1-C8-alkylaminocarbonyloxy;
- di-C1-C8-alkylaminocarbonyloxy;
- N—(C1-C8-alkyl)hydroxycarbamoyl;
- C1-C8-alkoxycarbamoyl;
- N—(C1-C8-alkyl)-C1-C8-alkoxycarbamoyl;
- aryl-C1-C8-alkylamino which is optionally substituted by up to 6 identical or different groups Rb;
- (C1-C8-alkoxyimino)-C1-C8-alkyl;
- (C2-C8-cycloalkoxyimino)-C1-C8 alkyl;
- C1-C8-alkyliminoxy;
- C1-C8-alkyliminoxy-C1-C8-alkyl;
- each of which is optionally substituted;
- or
- R1 and R2 can form together with the carbon to which they are attached a C3-C8-cycloalkyl;
- C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle;
- each of which is optionally substituted;
- or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc;
- or
- R3 and R4 can form together with the carbon to which they are attached a C3-C8-cycloalkyl;
- C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle;
- each of which is optionally substituted;
- or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc;
- or
- R5 and R6 can form together with the carbon to which they are attached a C3-C8-cycloalkyl;
- C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle;
- each of which is optionally substituted;
- or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc;
- or
- R7 and R8 can form together with the carbon to which they are attached a C3-C8-cycloalkyl;
- C3-C8-cycloalkenyl, or a saturated 5, 6 or 7 membered heterocycle;
- each of which is optionally substituted;
- or may represent a group ═C(Y1)Y2 or a group ═N—O—Rc or a group ═O;
- Y1 and Y2 independently of one another represent hydrogen, halogen, C1-C12-alkyl;
- C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms;
- C1-C8-alkylsulfanyl;
- phenyl;
- each of which is optionally substituted;
- or Y1 and Y2 can form together with the carbon to which they are attached a C3-C8-cycloalkyl or a C3-C8-cycloalkenyl or a saturated 5, 6 or 7 membered heterocycle;
- each of which is optionally substituted;
- Rb represents halogen;
- nitro, cyano, C1-C12-alkyl;
- C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms;
- C1-C6-alkoxy;
- C1-C6-haloalkoxy having 1 to 9 identical or different halogen atoms;
- C1-C6-alkylsulfanyl;
- C1-C6-haloalkylsulfanyl having 1 to 9 identical or different halogen atoms;
- C1-C6-alkyl sulfonyl;
- C1-C6-haloalkylsulfonyl having 1 to 9 identical or different halogen atoms;
- C2-C12-alkenyl;
- C2-C12-alkynyl;
- C3-C7-cycloalkyl;
- tri(C1-C8)alkylsilyl;
- Rc represents C1-C16-alkyl;
- C1-C6-haloalkyl having 1 to 9 identical or different halogen atoms;
- C3-C8-cycloalkyl;
- (C3-C8-cycloalkyl)-C1-C8-alkyl;
- (C3-C8-cycloalkyl)-C3-C8-cycloalkyl;
- C2-C8-alkenyl-C2-C8-alkynyl-C1-C16-alkyl;
- aryl-C1-C8-alkyl which is optionally substituted by up to 6 identical or different groups Rb;
- each of which is optionally substituted.
119 more elements
Dependencies are inferred from the claim text.