Method for producing amino acids
AssigneeBASF SE
InventorsChristian Gruenanger, Roland Bou Chedid, Markus Christian Biel, Johann-Peter Melder
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Abstract
Process for the preparation of alkali metal salts of glycine or of racemic α-amino acids of the general formula (I) R1—CH(NH2)—COOH (I) in which R1 is selected from hydrogen, CH3, C2H5, CH(CH3)2, (CH2)2COOH and CH2OH, wherein an alkali metal salt of the corresponding α-ketocarboxylic acid or glyoxalic acid is reacted in the presence of at least one heterogeneous catalyst, which comprises at least one transition metal, in the presence of hydrogen with at least one nitrogen compound at temperatures in the range from 50 to 200° C., where the nitrogen compound is selected from primary and secondary amines and ammonia.
Claims10
A process for preparing an alkali metal salt of a racemic α-amino acid of formula (I):
- R1—CH(NH2)—COOH (I),
- the process comprising reacting at least one nitrogen compound with an alkali metal salt of a corresponding α-ketocarboxylic acid or glyoxalic acid in the presence of at least one heterogeneous catalyst and hydrogen at a temperature ranging from 50 to 200° C., to form the alkali metal salt of the racemic α-amino acid of formula (I),
- wherein:
- R1 is a group selected from the group consisting of hydrogen, CH3, C2H5, CH(CH3), (CH2)2COOH and CH2OH;
- the heterogeneous catalyst comprises at least one transition metal;
- and
- the nitrogen compound is selected from the group consisting of a primary amine, a secondary amine and ammonia.
Dependencies are inferred from the claim text.