Multi-phased, biodegradable and oesteointegrative composite scaffold for biological fixation of musculoskeletal soft tissue to bone
AssigneeThe Trustees of Columbia University in the City of New York
InventorsHelen H. Lu, Jeffrey Spalazzi, Kathie Kionisio
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Abstract
Methods and apparatuses are provided for musculoskeletal tissue engineering. For example, a scaffold apparatus is provided which comprises microspheres of selected sizes and/or composition. The microspheres are layered to have a gradient of microsphere sizes and/or compositions. The scaffold provides a functional interface between multiple tissue types.
Claims4
A scaffold apparatus for musculoskeletal tissue engineering comprising a plurality of phases, wherein the apparatus has a gradient of mineral content across the phases, and at least one of the phases comprises a polymer-ceramic composite material.
Dependencies are inferred from the claim text.