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US 9,427,467 B2Granted
Hair removal with metal nanoparticles in surfactant containing solutions
AssigneeSienna Biopharmaceuticals, Inc.
InventorsTodd James Harris, Alice Ann Chen Kim
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Abstract
Treatment of skin tissue with photoactive materials and light, such as nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic applications to mammals such as humans. In particular, embodiments of hair removal with metal nanoparticles in surfactant containing solutions are disclosed.
Claims20
A method of localizing thermal damage to a hair follicle with a surfactant composition, comprising:
- topically applying a composition comprising a surfactant and nanoparticles to a skin surface;
- wherein the nanoparticles have at least one peak absorption wavelength selected from the group consisting of:
- 755 nm, 800-810 nm, and 1064 nm,
- wherein the nanoparticles have a concentration of 109 to 1016 particles per ml of the composition,
- wherein the nanoparticles comprise a conductive metal portion comprising at least one of gold, silver, and platinum,
- wherein the nanoparticles comprise a coating that coats the conductive metal portion;
- wherein the nanoparticles are unassembled,
- targeting a hair follicle by redistributing a portion of the composition of nanoparticles from the skin surface to the hair follicle while a remaining portion of the composition is left on the skin surface;
- removing the remaining portion of the composition from the skin surface while leaving the composition localized within the hair follicle;
- and
- irradiating the composition of nanoparticles with an energy source to induce a surface plasmon in said nanoparticles, thereby localizing thermal damage to said hair follicle.
8 more elements
A method of localizing thermal damage to a hair follicle with a surfactant composition, comprising:
- topically applying a composition comprising nanoparticles and a surfactant to a skin surface,
- wherein the nanoparticles comprise a conductive metal portion comprising at least one of gold, silver, and platinum,
- wherein the nanoparticles comprise a coating that coats the conductive metal portion;
- wherein the nanoparticles are unassembled,
- wherein the nanoparticles are provided in a range of 109 to 1016 particles in the composition;
- distributing a portion of the composition from the skin surface to a portion of a hair follicle while a remaining portion of the composition is left on the skin surface;
- removing the remaining portion of the composition from the skin surface while leaving the composition localized within the portion of the hair follicle;
- and
- exposing the composition to an energy wavelength selected from the group consisting of:
- 755 nm, 800-810 nm, and 1064 nm, thereby inducing a surface plasmon in said nanoparticles, thereby localizing thermal damage to said portion of the hair follicle.
7 more elements
A method of removing a hair follicle with a surfactant composition, comprising:
- applying a composition comprising a surfactant and nanoparticles to a skin surface,
- wherein the nanoparticles have a concentration of 109 to 1016 particles per ml of the composition, wherein the nanoparticles are unassembled,
- distributing a portion of the composition of from the skin surface to a portion of a hair follicle while a remaining portion of the composition is left on the skin surface;
- wherein the nanoparticles comprise a coating,
- wherein the nanoparticles comprise at least one of gold, silver, and platinum,
- removing the remaining portion of the composition from the skin surface, and
- exposing the composition of nanoparticles to an energy wavelength, thereby localizing thermal damage to said portion of the hair follicle.
4 more elements
Dependencies are inferred from the claim text.