Hypercholesterolemia and tendinous injuries
AssigneeThe Trustees of the University of Pennsylvania
InventorsJoseph A. Abboud, Louis J. Soslowsky
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Abstract
This invention provides compositions and methods of inhibiting, suppressing, or treating a tendinous or musculoskeletal soft tissue injury. The invention further provides a method of ameliorating symptoms associated with a tendinous or musculoskeletal soft tissue injury. Additionally, the invention provides methods for evaluating the risk of developing a tendinous or musculoskeletal soft tissue injury.
Claims23
A method of treating a tendinous or musculoskeletal soft tissue injury, in a subject with hypercholesterolemia, comprising systemically administering to said subject with hypercholesterolemia a therapeutically effective amount of a cholesterol lowering agent, wherein said soft tissue injury is a tendon injury, and wherein the cholesterol lowering agent is a statin.
A method of reducing the risk of recurrence of a tendon injury, in a subject with hypercholesterolemia who previously had said tendon injury, comprising systemically administering to said subject with hypercholesterolemia a therapeutically effective amount of a cholesterol lowering agent, and wherein the cholesterol lowering agent is a statin.
Dependencies are inferred from the claim text.