US 9,427,436 B1Granted

Compositions for treating CMT and related disorders

AssigneePharnext

InventorsDaniel Cohen, Serguei Nabirochkin, Ilya Chumakov

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The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders.

Dependent claims

A pharmaceutical composition comprising:

(i) baclofen or a salt thereof,
(ii) sorbitol or a salt thereof, and
(iii) naltrexone or a salt thereof;
in a relative weight ratio of the baclofen, sorbitol, and naltrexone of 8.6:300:1;
and a pharmaceutically suitable excipient or carrier.

2 more elements

Dependencies are inferred from the claim text.

A61K 31/485
Quinolines; Isoquinolines: morphinan derivatives, e.g. morphine, codeine
A61K 9/0053
Galenical forms characterised by the site of application: mouth and digestive tract, i.e. intraoral and peroral administration
A61K 31/047
Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates: having two or more hydroxy groups, e.g. sorbitol
A61K 31/192
Carboxylic acids, e.g. valproic acid: having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid

From the US filing history. Foreign family members aren’t listed.

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