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US 9,427,435 B2Granted
Narcotic emulsion formulations for treatment of cancer pain
AssigneesTeikoku Pharma USA, Inc., Techno Guard Co., Ltd.
InventorsKiichiro Nabeta, Toru Hibi
Life of this patent
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Abstract
Methods and compositions of treating a subject for cancer pain are provided. In the subject methods, a subject is treated for cancer pain by administering to the subject an effective amount of a narcotic emulsion, e.g., fentanyl elmulsion, formulation. In certain embodiments, the emulsion formulations include a narcotic active agent, oil, water and a surfactant. Also provided are methods of making the subject emulsion formulations as well as kits that include the emulsion formulations.
Claims12
An emulsion formulation comprising:
- 0.1-10 mg/ml fentanyl;
- 0.05-200 mg/ml Vegetable oil;
- water;
- 0.1-50 mg/ml natural phospholipid as surfactant;
- oleic acid as emulsification enhancer;
- and
- a stabilizing agent.
4 more elements
A kit comprising an emulsion formulation comprising:
- 0.1-10 mg/ml fentanyl;
- 0.05-200 mg/ml Vegetable oil;
- water;
- 0.1-50 mg/ml natural phospholipid as surfactant;
- oleic acid as emulsification enhancer;
- and
- a stabilizing agent.
4 more elements
Dependencies are inferred from the claim text.