Use of histone deacetylase inhibitors in changing MRJP3 protein in royal jelly
AssigneeNaturewise Biotech & Medicals Corporation
InventorsChung-Yang Huang, Chia-Nan Chen, Wei-Jung Chen, Wei-Jan Huang, Li-Ling Chi
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Abstract
The invention provides a method of changing a ratio of 68 to 64 kDa protein of MRJP3 in a royal jelly, a method of producing a royal jelly comprising MRJP3 having a changed ratio of 68 to 64 kDa protein relative to a control royal jelly and the royal jelly produced thereform. Also provided is a method of promoting the growth of the larva of a queen bee comprising feeding the larva of the queen bee a royal jelly of the invention. Further provided is a method of producing bee larva, pupa and queen bees with sizes larger than normal.
Claims12
A method of producing bee larvae that are at least 100% greater in weight than control larvae comprising feeding young worker bees a histone deacetylase (HDAC) inhibitor or a mixture of HDAC inhibitors and feeding bee larvae royal jelly secreted by these young worker bees, while the bee larvae of the control receive the royal jelly produced by young worker bees not fed with a HDAC inhibitor or a mixture HDAC inhibitors.
Dependencies are inferred from the claim text.