Synergistic microbicidal combinations
AssigneeRohm and Haas Company
InventorsMegan Anne Diehl, Eileen Fleck Warwick
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Abstract
Antimicrobial compositions based on the synergistic combination of 2-methyl-3-isothiazolone and selected commercial microbicides where the compositions are substantially free of halogenated 3-isothiazolone, are disclosed. Particularly preferred are combinations of 2-methyl-3-isothiazolone together with benzoic acid, citric acid, sorbic acid, 1,2-dibromo-2,4-dicyanobutane, 1,3-dimethylol-5,5-dimethylhydantoin, phenoxyethanol, benzyl alcohol, zinc pyrithione or climbazole, that provide enhanced microbicidal efficacy at a combined active ingredient level lower than that of the combined individual 3-isothiazolone and commercial microbicide effective use levels.
Claims4
A microbicidal composition consisting of 2-methyl-3-isothiazolone and sorbic acid which is effective for inhibiting growth of a microorganism selected from a bacteria or a mold, wherein either (a) the ratio of 2-methyl-3-isothiazolone to sorbic acid is from 1/4 to 1/20 and over such range that composition exhibits synergy for inhibiting growth of Staphylococcus aureus or (b) the ratio of 2-methyl-3-isothiazolone to sorbic acid is from 1/4 to 1/8, or 1/16 to 1/27 and over such range the composition exhibits synergy for inhibiting growth of Aspergillus niger.
Dependencies are inferred from the claim text.