Synergistic microbicidal combinations
AssigneeRohm and Haas Company
InventorsMegan Anne Diehl, Eileen Fleck Warwick
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Abstract
Antimicrobial compositions based on the synergistic combination of 2-methyl-3-isothiazolone and selected commercial microbicides where the compositions are substantially free of halogenated 3-isothiazolone, are disclosed. Particularly preferred are combinations of 2-methyl-3-isothiazolone together with benzoic acid, citric acid, sorbic acid, 1,2-dibromo-2,4-dicyanobutane, 1,3-dimethylol-5,5-dimethylhydantoin, phenoxyethanol, benzyl alcohol, zinc pyrithione or climbazole, that provide enhanced microbicidal efficacy at a combined active ingredient level lower than that of the combined individual 3-isothiazolone and commercial microbicide effective use levels.
Claims4
A microbicidal composition consisting of 2-methyl-3-isothiazolone and phenoxyethanol which is effective for inhibiting growth of a microorganism selected from a yeast or a bacteria, wherein either (a) the ratio of 2-methyl-3-isothiazolone to phenoxyethanol is from 1/2 to 1/6.4 and over such range that composition exhibits synergy for inhibiting growth of Candida albicans or (b) the ratio of 2-methyl-3-isothiazolone to phenoxyethanol is from 1/30 to 1/80 or 1/107 to 1/133 and over such range the composition exhibits synergy for inhibiting growth of Pseudomonas aeruginosa.
Dependencies are inferred from the claim text.