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US 9,414,596 B2Granted
Metalloenzyme inhibitor compounds
AssigneeViamet Pharmaceuticals, Inc.
InventorsWilliam J. Hoekstra, Robert J. Schotzinger, Stephen W. Rafferty
Life of this patent
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Abstract
The present disclosure describes compounds having agricultural fungicidal activity.
Claims21
A method of controlling a pathogen-induced disease in a plant that is at risk of being diseased from the pathogen comprising contacting one of the plant and an area adjacent to the plant with a composition of Formula (I) or a salt thereof, wherein:
- MBG is optionally substituted tetrazolyl, optionally substituted triazolyl, or optionally substituted pyrazolyl;
- R1 is H, halo, alkyl or haloalkyl;
- R2 is H, halo, alkyl or haloalkyl;
- each R3 is H, alkyl, cycloalkyl, cyano, haloalkyl, alkoxy, halo, haloalkoxy, alkoxyalkyl, haloalkoxyalkyl, aryloxyalkyl, thioalkyl, hydroxyl, halothioalkyl, thiocyanate, S(O)2R7, nitro, C(═O)CF3, C(═O)OR7, C(═O)NR7R8, amino, or cyclic amino, NHC(═O)CF3, or OCF2C(═O)OR7;
- R4 is aryl, heteroaryl, or cycloalkyl, optionally substituted with 0, 1, 2 or 3 independent R3;
- R5 is H, —P(O)(OH)2, —CH2—O—P(O)(OH)2, or —C(O)alkyl optionally substituted with amino;
- R6 is H, halo, alkyl, haloalkyl or haloalkoxy;
- R7 is alkyl or cycloalkyl;
- R8 is alkyl or haloalkyl;
- and
- n is 0, 1,2 or 3.
8 more elements
Dependencies are inferred from the claim text.