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US 9,410,963 B2Granted
Hexanoylglycine as biomarker for the predisposition for weight gain and obesity
AssigneeNestec S.A.
InventorsFrancois-Pierre Martin, Claire L. Boulange, Ivan Montoliu Roura, Sebastiano Collino, Marc-Emmanuel Dumas, Elaine Holmes, Serge Andre Dominique Rezzi, Jeremy Nicholson, Sunil Kochhar
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Abstract
The present invention relates generally to the field of nutrition and health. In particular, the present invention relates to a new biomarker, its use and a method that allows it to diagnose the likelihood to resist diet induced weight gain, and/or to be susceptible to a diet induced weight gain. For example, the biomarker may be hexanoylglycine.
Claims13
A method of diagnosing the likelihood of a subject to resist high fat diet induced weight gain, the method comprising:
- determining the level of hexanoylglycine in a urine sample previously obtained from a subject to be tested, and
- comparing the subject's hexanoylglycine level to a predetermined reference value,
- wherein the predetermined reference value is based on an average hexanoylglycine level in urine in a control population, and
- wherein an increased hexanoylglycine level in the sample compared to the predetermined reference value indicates an increased likelihood to resist high fat diet induced weight gain.
1 more element
Dependencies are inferred from the claim text.