Back to results
US 9,408,826 B2Granted
Isoflavone anti-viral compounds
AssigneeKineta, Inc.
InventorsShawn P. Iadonato, Kristin Bedard
Life of this patent
Estimating the term…
Abstract
Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.
Claims2
A pharmaceutical composition comprising a compound having a structure
- wherein
- R1 is selected from H, alkyl, or hydroxyl;
- R2 is selected from H or CF3;
- R3 is alkylsulfonyl;
- R4 is selected from H or lower alkyl;
- at least one R6 group is selected from CF3 or CO2R4;
- n is 0, 1, 2, or 3;
- p is 1, 2, 3, 4, or 5;
- and
- optionally, when p is 2 or more, at least one additional R6 group is selected from H, lower alkyl, aryl, alkoxy, heteroalkyl, heteroaryl, cyclic heteroalkyl, NH2, OH, CN, NO2, OCF3, CF3, Br, Cl, F, alkylcarbonyl, or alkylsulfonyl.
7 more elements
A pharmaceutical composition comprising a compound having a structure
- wherein R1 is selected from H, alkyl, or hydroxyl;
- R2 is selected from H or CF3;
- R3 is SO2R4;
- R4 is selected from H or lower alkyl;
- at least one R6 group is CF3;
- n is 0, 1, 2, or 3;
- p is 1, 2, 3, 4, or 5;
- and
- optionally, when p is 2 or more, at least one additional R6 group is selected from H, lower alkyl, aryl, alkoxy, heteroalkyl, heteroaryl, cyclic heteroalkyl, NH2, OH, CN, NO2, OCF3, CF3, Br, Cl, F, alkylcarbonyl, or alkylsulfonyl.
6 more elements
Dependencies are inferred from the claim text.