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US 9,404,922 B2Granted
Recombinant phages and proteins
AssigneeThe Rockefeller University
InventorsVincent Fischetti, Raymond Schuch, Sherry Kan
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Abstract
The present disclosure provides recombinant phages, a Wip1 p23 receptor binding protein and a Wip1 p24 receptor binding protein that bind to Bacillus anthracis. The disclosure further provides methods and uses thereof.
Claims4
A method of identifying or detecting Bacillus anthracis in a sample, the method comprising:
- (a) providing a sample suspected of containing Bacillus anthracis;
- (b) contacting the sample with a recombinant, Wip1 p23 receptor binding protein comprising the sequence of SEQ ID NO:23, wherein the recombinant Wip1 p23 receptor binding protein comprises a reporter molecule, the method comprising mixing the recombinant Wip1 p23 receptor binding protein and the sample to form a complex comprising the Wip1 p23 receptor binding protein and the Bacillus anthracis if the Bacillus anthracis is present, and
- detecting a signal from the reporter molecule in the complex to detect the presence of Bacillus anthracis in the sample.
Dependencies are inferred from the claim text.