Method of producing a multi-microchannel, flow-through element and device using same
AssigneeNew Mexico Tech Research Foundation
InventorsDmitri Ivniski, Vladimir Shapovalov
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Abstract
A method of producing a multi-microchannel, flow-through element, including the steps of providing a body of material, and producing multiple microchannels within the body, wherein the microchannels extend through the body to produce a multi-microchannel, flow-through element. Such an element can be used as a micromixer, a sensor element, a filter, a fuel element or a chromatographic element.
Claims11
A method of using a multi-microchannel, flow-through element as a transducer or electrode in an electrochemical sensor, comprising:
- applying a polarization potential between the multi-microchannel, flow-through element as a working electrode and a further, reference electrode;
- exposing the multi-microchannel, flow-through element to a sample containing an analyte;
- detecting as a signal a physico-chemical change as a result of interactions between the analyte in the sample and a complementary biorecognition agent, wherein said complementary biorecognition agent is immobilized in real time on at least one surface of the multi-microchannel flow-through element,
- wherein the multi-microchannel, flow-through element is provided for use in an electrochemical sensor, and wherein the multi-microchannel, flow-through element is provided as a transducer and is an electrically conductive, metallic element,
- wherein the multi-microchannel, flow-through element includes a body and a plurality of microchannels, wherein each of said microchannels extends completely through the body of the multi-microchannel, flow-through element and provides a direct flow path between opposite faces of said multi-microchannel, flow-through element.
A method of using a multi-microchannel, flow-through element as a transducer or electrode in an electrochemical sensor, comprising:
- applying a polarization potential between the multi-microchannel, flow-through element as a working electrode and a further, reference electrode;
- exposing the multi-microchannel, flow-through element to a sample containing an analyte;
- detecting as a signal a physico-chemical change as a result of interactions between the analyte in the sample and a complementary biorecognition agent immobilized on at least one surface of the multi-microchannel flow-through element,
- wherein the multi-microchannel, flow-through element is provided for use in an electrochemical sensor, and wherein the multi-microchannel, flow-through element is provided as a transducer and is an electrically conductive, metallic element, and
- wherein the electrochemical sensor is a flow-through micro-array chip that includes a carrier for said at least one multi-microchannel, flow-through element and a respective contact pad disposed on said carrier and electrically connected to said at least one multi-microchannel, flow-through element.
Dependencies are inferred from the claim text.