Antimicrobial non-adherent dressings and related methods therefor
AssigneeCovidien LP
InventorsAjit Moghe, Anand Kanchagar
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Abstract
A wound dressing comprising a substrate comprising a plurality of fibers, at least one antimicrobial agent in the substrate, and an oil emulsion on at least a portion of the substrate is disclosed. The at least one antimicrobial agent can be polyhexamethylene biguanide, and the oil emulsion can consist essentially of a petrolatum in a range of from about 75 wt % to about 90 wt % of the oil emulsion, a mineral oil in a range of from about 10 wt % to about 20 wt % of the oil emulsion, water in a range of from about 0.1 wt % to about 1 wt % of the oil emulsion, and at least one surfactant in a range of from about 1 wt % to about 5 wt % of the oil emulsion.
Claims13
A wound dressing comprising:
- a substrate comprising a plurality of fibers;
- at least one antimicrobial agent comprising a biguanide in the substrate, wherein the at least one antimicrobial agent is hydrophilic;
- and
- an oil emulsion impregnated throughout the entire substrate, wherein the oil emulsion consists essentially of:
- a petrolatum in a range of from about 75 wt % to about 90 wt % of the oil emulsion,
- a mineral oil in a range of from about 10 wt % to about 20 wt % of the oil emulsion,
- water in a range of from about 0.1 wt % to about 1 wt % of the oil emulsion, and
- at least one surfactant in a range of from about 1 wt % to about 5 wt % of the oil emulsion.
A method of preparing a wound dressing, comprising:
- applying at least one antimicrobial agent comprising a biguanide on a substrate comprising polymeric fibers, wherein the at least one antimicrobial agent is hydrophilic;
- and
- impregnating an oil emulsion throughout the entire substrate to produce the wound dressing, the oil emulsion consisting essentially of a petrolatum in a range of from about 75 wt % to about 90 wt % of the oil emulsion, a mineral oil in a range of from about 10 wt % to about 20 wt % of the oil emulsion, water in a range of from about 0.1 wt % to about 1 wt % of the oil emulsion, and at least one surfactant in a range of from about 1 wt % to about 5 wt % of the oil emulsion.
Dependencies are inferred from the claim text.