Implantable medical devices

An implantable medical device, comprising:

• a body including an external surface defining an outer profile of said device, said body further including:
• a porous matrix including a series of interconnected macropores defined by a plurality of interconnected struts, said struts each including a hollow interior, the porous matrix having a compressive strength of about 10 MPa and comprising a calcium based ceramic material defined by a compound that includes elements of calcium, oxygen and phosphorous, wherein a portion of at least one of said elements is substituted with an element having an ionic radius of about 0.1 to about 0.6 Å;
• a filler material substantially filling at least a portion of said series of interconnected macropores while not filling the hollow interior of each strut, the filler material comprising a polymeric material selected from the group consisting of polyetheretherketone (PEEK), carbon-reinforced PEEK, and polyetherketoneketone (PEKK);
• and
• a plurality of openings extending through at least a portion of said external surface and communicating with said hollow interior of at least a portion of said plurality of interconnected struts.

An implantable medical device, comprising a body including an external surface defining an outer profile of said device, said external surface including one or more exposed areas of a porous matrix including one or more interconnected openings defined by a plurality of interconnected struts, said struts each including a hollow interior upon implantation of said device, said body further including a biologically stable filler material substantially filling at least a portion of said one or more interconnected openings while not filling said hollow interiors of said interconnected struts, wherein post-implantation said matrix undergoes a remodeling process in which osteoclast activity progressively removes portions of said matrix and osteoblast activity progressively replaces said portions of said matrix with new bone tissue, and initiation of said remodeling process is limited to said one or more exposed areas of said matrix,

• wherein the porous matrix having a compressive strength of about 10 MPa and comprises a calcium based ceramic material defined by a compound that includes elements of calcium, oxygen and phosphorous, wherein a portion of at least one of said elements is substituted with an element having an ionic radius of about 0.1 to about 0.6 Å, and wherein the biologically stable filler material comprises a polymeric material selected from the group consisting of polyetheretherketone (PEEK), carbon-reinforced PEEK, and polyetherketoneketone (PEKK).

An implantable medical device, comprising:

• a body configured for positioning between a first vertebral body and a second vertebral body adjacent to the first vertebral body, the body including an external surface defining an outer profile of said device, said outer profile including a D-shape configured for positioning in a disc space between the first and second vertebral bodies, the external surface including a top portion and a bottom portion oppositely positioned, the top and bottom portions having projections configured to engage with the first and second vertebral bodies and resist expulsion of said device, the outer profile including sidewalls extending around and enclosing a hollow chamber configured for a bone growth enhancing material, said body further including:
• a bioresorbable ceramic matrix having a compressive strength of about 10 MPa and including a series of interconnected macropores defined by a plurality of interconnected struts, said interconnected struts each including a hollow interior, said hollow interiors defining interconnected passages that are hollow upon implantation of said device, said interconnected passages being isolated from said series of interconnected macropores, the bioresorbable ceramic matrix comprising a calcium based ceramic material defined by a compound that includes elements of calcium, oxygen and phosphorous, wherein a portion of at least one of said elements is substituted with an element having an ionic radius of about 0.1 to about 0.6 Å;
• a biologically stable polymeric material infused throughout and substantially filling said series of interconnected macropores;
• and
• wherein said plurality of interconnected passages are substantially free of said polymeric material.