Blood perfusion system

An extracorporeal blood perfusion system for receiving venous blood from a patient and for returning oxygenated blood to the patient in a cardiopulmonary bypass procedure, comprising:

• a disposable assembly including a cartridge and a plurality of interconnected tubing lines, the cartridge having one or more sensor stations and a plurality of internal fluid passageways, wherein a first of the tubing lines is fluidly interconnected with at least one of the plurality of fluid passageways, wherein the disposable assembly comprises an oxygenator connected in a blood circuit, wherein the disposable assembly defines the blood circuit for receiving venous blood from the patient and transferring oxygenated blood to the patient in a cardiopulmonary bypass procedure, and wherein the disposable assembly further comprises a reservoir having an inlet connected to receive venous blood from the patient through a second of the positioned tubing lines;
• and
• a control unit having a component interface region, the component interface region including a cartridge interface region that includes one or more sensors, wherein the cartridge interface region receives the cartridge and aligns the one or more sensors of the cartridge interface region with the one or more sensor stations on the cartridge, a first pump for operatively interfacing with the blood circuit, wherein the venous blood is pumped through the blood circuit by the first pump, a flow control clamp for controlling the flow of venous blood through the second tubing line to the reservoir, and at least one blood flow sensor for monitoring the flow of venous blood and that is capable of sending a control signal to trigger the flow control clamp.