System for emulsion aspiration
AssigneeBio-Rad Laboratories, Inc.
InventorsAdam Bemis, Thomas H. Cauley, III, Klint Rose, James M. Hamilton
Life of this patent
Estimating the term…
Abstract
System, including apparatus and methods, for aspirating at least a portion of an emulsion from a well using a tip. In some embodiments, the tip may have a flat end and an inlet surrounded by the flat end. The well may have a floor with one or more surface features that prevent uninterrupted circumferential contact of the flat end of the tip with any region of the floor. In some embodiments, the tip may not have a flat end. In some embodiments, the well may have a port that guides the tip to the floor with the tip slanted with respect to the floor. Methods of making a device that includes the well are also disclosed.
Claims17
A device for forming and holding an emulsion to be at least partially aspirated into a tip of a fluid-aspiration device, the tip having a flat end surrounding an inlet, the device comprising:
- a sample input channel;
- one or more carrier input channels;
- a droplet output channel;
- a droplet generation region configured to form droplets of an emulsion, the droplet generation region being created where the sample input channel, the one or more carrier input channels, and the droplet output channel meet one another;
- and
- an outlet well fluidically connected to the droplet generation region via the droplet output channel, the outlet well including a floor having one or more surface features that prevent uninterrupted circumferential contact of the flat end of the tip with the floor.
A device for forming and holding an emulsion, comprising:
- a sample input channel;
- one or more carrier input channels;
- a droplet output channel;
- a droplet generation region configured to form droplets of an emulsion, the droplet generation region being created where the sample input channel, the one or more carrier input channels, and the droplet output channel meet one another;
- and
- an outlet well fluidically connected to the droplet generation region via the droplet output channel and configured to collect droplets of the emulsion, the well having a floor facing upward and a side wall region extending upward from the floor, wherein the floor defines a projection.
Dependencies are inferred from the claim text.