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US 9,388,419 B2Granted
Methods for producing 3-hydroxypropionic acid and other products
AssigneesCargill, Incorporated, The Regents of the University of Colorado, a body corporate
InventorsMichael D. Lynch, Ryan T. Gill, Tanya E. W. Lipscomb
Life of this patent
Estimating the term…
Abstract
This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a chemical product, which includes 3-hydroxypropionic acid.
Claims19
A method for making acrylic acid, comprising:
- (a) producing 3-HP with a genetically modified microorganism comprising one or more heterologous nucleic acid sequences for increasing enzymatic activity in the malonyl-CoA reductase pathway and increasing enzymatic activity in the acetyl-CoA carboxylase pathway of said microorganism;
- and
- (b) converting said 3-HP produced by said genetically modified microorganism to acrylic acid.
Dependencies are inferred from the claim text.